Evidence map›Paper›PMID 29082129›Full record

ArticleBiochimie open2017

Subcellular localization of the five members of the human steroid 5α-reductase family.

Antonella Scaglione, Linda Celeste Montemiglio, Giacomo Parisi, Italia Anna Asteriti, Renato Bruni, Gabriele Cerutti, Claudia Testi, Carmelinda Savino, Filippo Mancia, Patrizia Lavia and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochimie open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
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  5. A novel pathogenic variant ofClinical case reports · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 2 countries.

Antonella ScaglioneDept. of Biochemical Sciences, Sapienza University of Rome, P.le A.Moro 5, 00185, Rome, Italy.
Linda Celeste MontemiglioDept. of Biochemical Sciences, Sapienza University of Rome, P.le A.Moro 5, 00185, Rome, Italy.
Giacomo ParisiDept. of Biochemical Sciences, Sapienza University of Rome, P.le A.Moro 5, 00185, Rome, Italy.
Italia Anna AsteritiCNR-IBPM P.le A.Moro 5, 00185, Rome, Italy.
Renato BruniNew York Consortium on Membrane Protein Structure, New York, NY 10027, USA.
Gabriele CeruttiDept. of Biochemical Sciences, Sapienza University of Rome, P.le A.Moro 5, 00185, Rome, Italy.
Claudia TestiCenter for Life Nano Science@Sapienza, IIT, V.le Regina Elena 291, Rome I-00185, Italy.
Carmelinda SavinoCNR-IBPM P.le A.Moro 5, 00185, Rome, Italy.
Filippo ManciaDepartment of Physiology and Cellular Biophysics, Columbia University, New York, NY 10032, USA.
Patrizia LaviaCNR-IBPM P.le A.Moro 5, 00185, Rome, Italy.
Beatrice ValloneDept. of Biochemical Sciences, Sapienza University of Rome, P.le A.Moro 5, 00185, Rome, Italy.
Institute of Molecular Biology and Pathology · ITSapienza University of Rome · ITAmerican Academy in Rome · USCenter for Nano Science and Technology · ITColumbia University · USIstituto Pasteur · ITNew York Structural Biology Center · US

Funding

Structural Genomics on Membrane ProteinsU54GM095315 · NIGMS · NEW YORK STRUCTURAL BIOLOGY CENTER · PI ROST, BURKHARD · 2010 to 2014
$15.2M
Training (303-338)P41GM116799 · NIGMS · NEW YORK STRUCTURAL BIOLOGY CENTER · PI HENDRICKSON, WAYNE A. · 2016 to 2020
$7.1M
Lipid biosynthesis and modification by integral-membrane enzymesR01GM111980 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MANCIA, FILIPPO · 2015 to 2018
$2.2M
NIGMS NIH HHS P41 GM116799NIGMS NIH HHS R01 GM111980NIGMS NIH HHS U54 GM095315
6 · The paper itself

Abstract

In humans the steroid 5alpha-reductase (SRD5A) family comprises five integral membrane enzymes that carry out reduction of a double bond in lipidic substrates: Δ

Indexed as

polyprenol reductaseSteroid 5alpha-reductasesubcellular localizationtrans-enoyl-CoA reductase

Identifiers

PMID29082129
PMCPMC5656259
OpenAlexW2597881891

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.