Evidence map›Paper›PMID 29082114›Full record

ArticleCurrent pathobiology reports2017

An interspecies heart-to-heart: Using

Alexandra MacColl Garfinkel, Mustafa K Khokha

Abstract read
In one paragraph

Article in Current pathobiology reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Use of Frogs as a Model to Study the Etiology of HLHS.Journal of cardiovascular development and disease · 2023
    Article
  8. Article
  9. Article
  10. Cold Spring Harbor perspectives in biology · 2020
    Review
  11. Heart Development and Regeneration in Non-mammalian Model Organisms.Frontiers in cell and developmental biology · 2020
    Review
  12. Article
  13. Frontiers in physiology · 2019
    Review
  14. The Many Faces ofFrontiers in physiology · 2019
    Article
  15. Xenbase: Facilitating the Use ofFrontiers in physiology · 2019
    Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alexandra MacColl GarfinkelPediatric Genomics Discovery Program, Departments of Pediatrics and Genetics; Yale University School of Medicine.
Mustafa K KhokhaPediatric Genomics Discovery Program, Departments of Pediatrics and Genetics; Yale University School of Medicine.
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
New Mechanisms of Heterotaxy and Congenital Heart Disease: Nucleoporins at CiliaR01HL124402 · NHLBI · YALE UNIVERSITY · PI KHOKHA, MUSTAFA K, LUSK, CHARLES PATRICK · 2015 to 2022
$5.5M
A system approach to the analysis of Heterotaxy Candiate GenesR01HD081379 · NICHD · YALE UNIVERSITY · PI KHOKHA, MUSTAFA K · 2014 to 2018
$2.7M
Cardiac phenotyping of CHD candidate genes in XenopusR33HL120783 · NHLBI · YALE UNIVERSITY · PI BRUECKNER, MARTINA, KHOKHA, MUSTAFA K · 2016 to 2018
$1.6M
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS R01 HL124402NHLBI NIH HHS R33 HL120783NICHD NIH HHS R01 HD081379
6 · The paper itself

Abstract

purpose of reviewGiven the enormous impact congenital heart disease has on child health, it is imperative that we improve our understanding of the disease mechanisms that underlie patient phenotypes and clinical outcomes. This review will outline the merits of using the frog model, RECENT

findingsPatient-driven gene discovery continues to provide new insight into the mechanisms of congenital heart disease, and by extension, patient phenotypes and outcomes. By identifying gene variants in CHD patients, studies in SUMMARY: Analyses in model organisms can help to elucidate the disease mechanisms underlying CHD patient phenotypes. Using

Indexed as

congenital heart diseaseCRISPR/Cas9heterotaxyleft-right patterningXenopus

Identifiers

PMID29082114
PMCPMC5658036
OpenAlexW2611502707

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.