ArticleBiomedical optics express2017
Optophysiology of cardiomyocytes: characterizing cellular motion with quantitative phase imaging.
Article in Biomedical optics express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Morphological investigation of astrocyte brain cells using quantitative phase imaging.Biomedical optics express · 2026Article
- Rotating Gold Nanomotors for High-Resolution Mapping of Subcellular Nanomotions.Small methods · 2025Article
- Reflective lens-free imaging on high-density silicon microelectrode arrays for monitoring and evaluation ofBiomedical optics express · 2018Article
- Interferometric mapping of material properties using thermal perturbation.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
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Authors and funding
7 authors.
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Abstract
Quantitative phase imaging enables precise characterization of cellular shape and motion. Variation of cell volume in populations of cardiomyocytes can help distinguish their types, while changes in optical thickness during beating cycle identify contraction and relaxation periods and elucidate cell dynamics. Parameters such as characteristic cycle shape, beating frequency, duration and regularity can be used to classify stem-cell derived cardiomyocytes according to their health and, potentially, cell type. Unlike classical patch-clamp based electrophysiological characterization of cardiomyocytes, this interferometric approach enables rapid and non-destructive analysis of large populations of cells, with longitudinal follow-up, and applications to tissue regeneration, personalized medicine, and drug testing.
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