Evidence map›Paper›PMID 29082038›Full record

ArticleJournal of ophthalmology2017

Phenotypic Description of the Spanish Multicentre Genetic Glaucoma Group Cohort.

Elena Milla, Maria José Gamundi, Susana Duch, Jose Rios, Miguel Carballo, Emeigg Study Group

Open access · goldAbstract read
In one paragraph

Article in Journal of ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Elena MillaUnidad de Glaucoma, Institut Clínic d'Oftalmologia (ICOF), Hospital Clínic, Barcelona, Spain.ORCID 0000-0002-5171-165X
Maria José GamundiServicio de Laboratorio, Hospital de Terrassa, Barcelona, Spain.
Susana DuchUnidad de Glaucoma y Genética, Institut Comtal d'Oftalmologia, Barcelona, Spain.
Jose RiosServicio de Estadística, Hospital Clinic, Barcelona, Spain.
Miguel CarballoServicio de Laboratorio, Hospital de Terrassa, Barcelona, Spain.
Emeigg Study GroupEMEIGG, Spanish Multicentre Glaucoma Group (Estudio Multicéntrico Español de Investigaciones Genéticas en Glaucoma), Spain.
Hospital Clínic de Barcelona · ESHospital Terrassa · ESSpanish Ovarian Cancer Research Group · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of the study was to make a phenotypic description of the Spanish multicentre glaucoma group cohort of patients.

designRetrospective, observational, multicentre, cohort study. MATERIAL AND

methodsThe clinical charts of 152 patients with hereditary glaucoma from18 Spanish eye centres were reviewed in order to make an epidemiologic description of the type of glaucoma and associated factors. True hereditary cases were compared with familiar cases according to the Gong et al. criteria.

results61% were true hereditary cases and 39% familiar cases. Ocular comorbidity, optic disc damage, and visual field mean defect were significantly more severe in hereditary patients, who required significantly more first-line hypotensive drugs and surgical interventions to control intraocular pressure than familiar patients.

conclusionsThe strength of the hereditary component of glaucoma seems to worsen the clinical course, causing more structural and functional damage and requiring more intense glaucoma treatment. The family history of glaucoma should be carefully investigated and taken into consideration when making treatment decisions or intensifying previous treatment.

Identifiers

PMID29082038
PMCPMC5634567
OpenAlexW2757348797

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.