Evidence map›Paper›PMID 29081982›Full record

ArticleNPJ biofilms and microbiomes2017

The making of a miscreant: tobacco smoke and the creation of pathogen-rich biofilms.

Samir A Shah, Sukirth M Ganesan, Saradhadevi Varadharaj, Shareef M Dabdoub, John D Walters, Purnima S Kumar

Open access · goldAbstract read
In one paragraph

Article in NPJ biofilms and microbiomes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 41 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Review
  5. Article
  6. Diet type and the oral microbiome.Frontiers in nutrition · 2025
    Review
  7. Review
  8. Observational
  9. Article
  10. Article
  11. Tobacco smoke exacerbates Filifactor alocis pathogenicity.Journal of clinical periodontology · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Microbiology of the American Smokeless Tobacco.Applied microbiology and biotechnology · 2021
    Review
  16. The dental plaque biofilm matrix.Periodontology 2000 · 2021
    Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Samir A ShahDivision of Periodontology, College of Dentistry, The Ohio State University, 4111 Postle Hall. 305, W 12th Avenue, Columbus, OH 43210 USA.
Sukirth M GanesanDivision of Periodontology, College of Dentistry, The Ohio State University, 4111 Postle Hall. 305, W 12th Avenue, Columbus, OH 43210 USA.
Saradhadevi VaradharajDavis Heart Lung Research Institute, The Ohio State University, Columbus, OH USA.
Shareef M DabdoubDivision of Periodontology, College of Dentistry, The Ohio State University, 4111 Postle Hall. 305, W 12th Avenue, Columbus, OH 43210 USA.ORCID 0000-0002-1374-8347
John D WaltersDivision of Periodontology, College of Dentistry, The Ohio State University, 4111 Postle Hall. 305, W 12th Avenue, Columbus, OH 43210 USA.
Purnima S KumarDivision of Periodontology, College of Dentistry, The Ohio State University, 4111 Postle Hall. 305, W 12th Avenue, Columbus, OH 43210 USA.ORCID 0000-0001-5844-1341
The Ohio State University · USLung Institute · USNew Jersey Commission on Science, Innovation and Technology · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Tasleem J Padamsee · 1985 to 2026
$132.3M
Tobacco smoking and perturbations in the subgingival microbial ecosystemR01DE022579 · NIDCR · OHIO STATE UNIVERSITY · PI KUMAR, PURNIMA · 2012 to 2016
$1.9M
NCI NIH HHS P30 CA016058NIDCR NIH HHS R01 DE022579
6 · The paper itself

Abstract

We have previously reported that oral biofilms in clinically healthy smokers are pathogen-rich, and that this enrichment occurs within 24 h of biofilm formation. The present investigation aimed to identify a mechanism by which smoking creates this altered community structure. By combining in vitro microbial-mucosal interface models of commensal (consisting of

Identifiers

PMID29081982
PMCPMC5655325
OpenAlexW2767057995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.