ArticleChemical science2017
Enantioselective Nazarov cyclization of indole enones cooperatively catalyzed by Lewis acids and chiral Brønsted acids.
Article in Chemical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 62 citations in OpenAlex.
- Taming the reactive intermediates: the nazarov cyclization as a programmable platform.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026Review
- Bismuth(III) triflate: an economical and environmentally friendly catalyst for the Nazarov reaction.Beilstein journal of organic chemistry · 2024Article
- Asymmetric Gold(I)-Catalyzed Tandem Hydroarylation-Nazarov Cyclization: Enantioselective Access to Cyclopentenones.Angewandte Chemie (International ed. in English) · 2022Article
- Enyne diketones as substrate in asymmetric Nazarov cyclization for construction of chiral allene cyclopentenones.Nature communications · 2022Article
- Stereodivergent synthesis of enantioenriched azepino[3,4,5-Chemical science · 2022Article
- Hydrogen radical-shuttle (HRS)-enabled photoredox synthesis of indanones via decarboxylative annulation.Nature communications · 2021Article
- Strong and Confined Acids Enable a Catalytic Asymmetric Nazarov Cyclization of Simple Divinyl Ketones.Journal of the American Chemical Society · 2019Article
- Enantioselective Synthesis of Chiral Cyclopent-2-enones by Nickel-Catalyzed Desymmetrization of Malonate Esters.Angewandte Chemie (International ed. in English) · 2018Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Enantioselective control of the chirality of a tertiary α-carbon in the products of a Nazarov cyclization of enones is challenging because the reaction involves an enantioselective proton transfer process. We herein report the use of cooperative catalysis using Lewis acids and chiral Brønsted acids to control the stereochemistry of the tertiary α-carbon in the products of this reaction. Specifically, with ZnCl
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.