Evidence map›Paper›PMID 29081908›Full record

ArticleWorld journal of cardiology2017

Utility and correlation of known anticoagulation parameters in the management of pediatric ventricular assist devices.

Ajay K Bhatia, Mouhammad Yabrodi, Mallory Carroll, Silvia Bunting, Kirk Kanter, Kevin O Maher, Shriprasad R Deshpande

Abstract read
In one paragraph

Article in World journal of cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. An introduction to point-of-care testing in extracorporeal circulation and LVADs.Hematology. American Society of Hematology. Education Program · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ajay K BhatiaDivision of Pediatric Cardiology, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA 30322, United States.
Mouhammad YabrodiDivision of Pediatric Cardiology, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA 30322, United States.
Mallory CarrollMechanical Circulatory Support Program, Children's Healthcare of Atlanta, Atlanta, GA 30322, United States.
Silvia BuntingDepartment of Pathology, Emory University School of Medicine, Atlanta, GA 30322, United States.
Kirk KanterDepartment of Cardiothoracic Surgery, Emory University School of Medicine, Atlanta, GA 30322, United States.
Kevin O MaherDivision of Pediatric Cardiology, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA 30322, United States.
Shriprasad R DeshpandeDivision of Pediatric Cardiology, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA 30322, United States. deshpandes@kidsheart.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo assess utility and correlation of known anticoagulation parameters in the management of pediatric ventricular assist device (VAD).

methodsRetrospective study of pediatric patients supported with a Berlin EXCOR VAD at a single pediatric tertiary care center during a single year.

resultsWe demonstrated associations between activated thromboplastin time (aPTT) and R-thromboelastography (R-TEG) values (rs = 0.65,

conclusionThis study suggests that while there is strong correlation between aPTT, anti-Xa assay and R-TEG values for patients requiring VAD support, there is a lack of relevant correlation between heparin dose and degree of effect. This raises concern as various guidelines continue to recommend using these parameters to titrate heparin therapy.

Indexed as

AnticoagulationBERLIN-EXCORPediatricThromboelastographyVentricular assist device

Identifiers

PMID29081908
PMCPMC5633539

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.