ReviewWorld journal of cardiology2017
Takotsubo cardiomyopathy: Pathophysiology and role of cardiac biomarkers in differential diagnosis.
Review in World journal of cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Takotsubo cardiomyopathy with low ventricular ejection fraction and apical ballooning predicts mortality: a systematic review and meta-analysis.Heart failure reviews · 2021Pooled it
- Takotsubo cardiomyopathy concurrent with hyperthyroidism following COVID-19-a case report and literature review.Frontiers in cardiovascular medicine · 2026Article
- Article
- Early detection of acute coronary syndrome using traditional versus emerging biochemical markers.Bioinformation · 2025Article
- Reply to Letter to the Editor: 'Recurrent Cardiac Myxoma: A Puzzle to be Solved'.Anatolian journal of cardiology · 2023Article
- Sudden cardiac arrest due to recurrent coronary spasm in a young woman: a case report.European heart journal. Case reports · 2023Article
- Diagnosis and Management of Takotsubo Syndrome in Acute Aneurysmal Subarachnoid Hemorrhage: A Comprehensive Review.Reviews in cardiovascular medicine · 2023Review
- Takotsubo cardiomyopathy as an overlooked cause of cardiac arrest in a patient undergoing ureteral stenting: a case report and literature review.The Journal of international medical research · 2022Review
- Trigger related outcomes of takotsubo syndrome in a cancer population.Frontiers in cardiovascular medicine · 2022Article
- Inverted Takotsubo Syndrome With HELLP Syndrome: A Case Report.Frontiers in cardiovascular medicine · 2022Article
- Early Differentiation of Stress Cardiomyopathy from Acute Anterior Wall Myocardial Using Changing Cardiac Enzyme Patterns.Journal of cardiovascular imaging · 2021Article
- Current Knowledge and Future Challenges in Takotsubo Syndrome: Part 1-Pathophysiology and Diagnosis.Journal of clinical medicine · 2021Review
- Takotsubo Syndrome: Clinical Manifestations, Etiology and Pathogenesis.Current cardiology reviews · 2021Article
- Takotsubo Syndrome: Optimizing Care with a Multidisciplinary Approach.Journal of multidisciplinary healthcare · 2021Review
- Seizure-Associated Takotsubo Cardiomyopathy.Cureus · 2020Article
- Sex Differences Across the Lifespan: A Focus on Cardiometabolism.Journal of women's health (2002) · 2020Article
- 2-Year follow-up of a patient with CD36 deficiency and takotsubo cardiomyopathy.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Takotsubo syndrome: The past, the present and the future.World journal of cardiology · 2019Article
- Under-diagnosis of Takotsubo Cardiomyopathy Increases Risk of Adverse Events: A Case Study.Cureus · 2019Article
- Forme Fruste in Recurring Mid-Ventricular Variant of Takotsubo Cardiomyopathy.The American journal of case reports · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Takotsubo cardiomyopathy (TC) is characterized by reversible ventricular dysfunction, not limited to the distribution of an epicardial coronary artery. A disease primarily afflicting post-menopausal women, it is frequently mistaken for acute anterior wall myocardial infarction. Alternatively called Stress Cardiomyopathy, physical or emotional triggers are identified in only three fourths of TC patients. Long considered a benign condition, recent findings suggest poor short term prognosis similar to acute coronary syndrome (ACS). Despite the widely recognized pathophysiological role of catecholamine excess, its diagnostic role is uncertain. TC is suspected based on typical wall motion abnormalities in ventriculogram or echocardiogram. Several additional electrocardiographic, laboratory and imaging parameters have been studied with the goal of clinical diagnosis of TC. While several clinical clues differentiate it from ACS, a clinical diagnosis is often elusive leading to avoidable cardiac catheterizations. Natriuretic peptides (NPs), a family of peptide hormones released primarily in response to myocardial stretch, play a significant role in pathophysiology, diagnosis as well as treatment of congestive heart failure. TC with its prominent ventricular dysfunction is associated with a significant elevation of NPs. NPs are elevated in ACS as well but the degree of elevation is typically lesser than in TC. Markers of myocardial injury such as troponin are usually elevated to a higher degree in ACS than in TC. This differential elevation of NPs and markers of myocardial injury may play a role in early clinical recognition of TC.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.