Evidence map›Paper›PMID 29081890›Full record

ArticleOxidative medicine and cellular longevity2017

Role of Diet and Nutritional Supplements in Parkinson's Disease Progression.

Laurie K Mischley, Richard C Lau, Rachel D Bennett

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 2 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 2 syntheses or guidelines pooled it, 168 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Low-fat versus ketogenic diet in Parkinson's disease: A pilot randomized controlled trial.Movement disorders : official journal of the Movement Disorder Society · 2018
    Trial
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Lifestyle medicine in Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  13. Article
  14. Review
  15. Early-Onset Parkinson's Disease: Unique Features and Management Approaches.Current neurology and neuroscience reports · 2025
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Laurie K MischleyBastyr University Research Institute, 14500 Juanita Dr. NE, Kenmore, WA 98028, USA.ORCID 0000-0003-1166-6978
Richard C LauOregon State University, 101 Milam Hall, Corvallis, OR 97331, USA.
Rachel D BennettBastyr University Research Institute, 14500 Juanita Dr. NE, Kenmore, WA 98028, USA.
Bastyr University · USOregon State University · US

Funding

Intranasal Glutathione in Parkinson's DiseaseK01AT004404 · NCCIH · BASTYR UNIVERSITY · PI MISCHLEY, LAURIE KATHERN · 2010 to 2014
$589k
NCCIH NIH HHS K01 AT004404
6 · The paper itself

Abstract

objectivesThe goal of this study is to describe modifiable lifestyle variables associated with reduced rate of Parkinson's disease (PD) progression.

methodsThe patient-reported outcomes in PD (PRO-PD) were used as the primary outcome measure, and a food frequency questionnaire (FFQ) was used to assess dietary intake. In this cross-sectional analysis, regression analysis was performed on baseline data to identify the nutritional and pharmacological interventions associated with the rate of PD progression. All analyses were adjusted for age, gender, and years since diagnosis.

results1053 individuals with self-reported idiopathic PD were available for analysis. Foods associated with the reduced rate of PD progression included fresh vegetables, fresh fruit, nuts and seeds, nonfried fish, olive oil, wine, coconut oil, fresh herbs, and spices ( DISCUSSION: These are the first data to provide evidence that targeted nutrition is associated with the rate of PD progression.

Indexed as

DietDietary SupplementsDisease ProgressionFemaleHumansMaleMiddle AgedParkinson Disease

Identifiers

PMID29081890
PMCPMC5610862
OpenAlexW2753639239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.