Evidence map›Paper›PMID 29081886›Full record

ArticleOxidative medicine and cellular longevity2017

Expression and Role of the Calcium-Sensing Receptor in Rat Peripheral Blood Polymorphonuclear Neutrophils.

Tai-Yu Zhai, Bao-Hong Cui, Lei Zou, Jing-Ya Zeng, Song Gao, Qianyu Zhao, Yuan Wang, Wan-Lin Xie, Yi-Hua Sun

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

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  12. Prokineticin 2Frontiers in immunology · 2020
    Article
  13. Review
  14. Clinical Impact of p27Endocrine pathology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Tai-Yu ZhaiDepartment of Clinical Laboratory, Harbin Medical University Cancer Hospital, Harbin 150086, China.
Bao-Hong CuiDepartment of Clinical Laboratory, Harbin Medical University Cancer Hospital, Harbin 150086, China.
Lei ZouDepartment of Clinical Laboratory, Harbin Medical University Cancer Hospital, Harbin 150086, China.
Jing-Ya ZengDepartment of Clinical Laboratory, Harbin Medical University Cancer Hospital, Harbin 150086, China.
Song GaoDepartment of Clinical Laboratory, Harbin Medical University Cancer Hospital, Harbin 150086, China.
Qianyu ZhaoDepartment of Clinical Laboratory, Harbin Medical University Cancer Hospital, Harbin 150086, China.
Yuan WangDepartment of Clinical Laboratory, Harbin Medical University Cancer Hospital, Harbin 150086, China.
Wan-Lin XieDepartment of Clinical Laboratory, Harbin Medical University Cancer Hospital, Harbin 150086, China.
Yi-Hua SunDepartment of Clinical Laboratory, Harbin Medical University Cancer Hospital, Harbin 150086, China.ORCID 0000-0001-8027-2927
Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The calcium-sensing receptors (CaSRs) play an important role in many tissues and organs that are involved in inflammatory reactions. Peripheral blood polymorphonuclear neutrophils (PMNs) are important inflammatory cells. However, the expression and functions of CaSR in peripheral blood PMNs are still not reported. In this study, we collected rat peripheral blood PMNs to observe the relationship between CaSR and PMNs. From the results, we found first that the CaSR protein was expressed in PMNs, and it increased after PMNs were activated with fMLP. In addition, CaSR activator cincalcet promoted the expression of CaSR and P-p65 (NF-

Indexed as

AnimalsNeutrophilsRatsRats, WistarReceptors, Calcium-SensingReceptors, Calcium-Sensing

Identifiers

PMID29081886
PMCPMC5610836
OpenAlexW2750669647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.