Evidence map›Paper›PMID 29081775›Full record

ArticleFrontiers in immunology2017

LFA-1 Mediates Cytotoxicity and Tissue Migration of Specific CD8

Camila Pontes Ferreira, Leonardo Moro Cariste, Fernando Dos Santos Virgílio, Barbara Ferri Moraschi, Caroline Brandão Monteiro, Alexandre M Vieira Machado, Ricardo Tostes Gazzinelli, Oscar Bruna-Romero, Pedro Luiz Menin Ruiz, Daniel Araki Ribeiro and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Frontiers in cellular and infection microbiology · 2023
    Article
  4. Review
  5. Rapamycin Improves the Response of Effector and Memory CD8Frontiers in cellular and infection microbiology · 2021
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Camila Pontes FerreiraMolecular Immunology Laboratory, Center of Molecular and Cellular Therapy, São Paulo, Brazil.
Leonardo Moro CaristeMolecular Immunology Laboratory, Center of Molecular and Cellular Therapy, São Paulo, Brazil.
Fernando Dos Santos VirgílioMolecular Immunology Laboratory, Center of Molecular and Cellular Therapy, São Paulo, Brazil.
Barbara Ferri MoraschiMolecular Immunology Laboratory, Center of Molecular and Cellular Therapy, São Paulo, Brazil.
Caroline Brandão MonteiroDepartment of Biosciences, Federal University of São Paulo, São Paulo, Brazil.
Alexandre M Vieira MachadoRené Rachou Research Center, Fiocruz, Minas Gerais, Brazil.
Ricardo Tostes GazzinelliRené Rachou Research Center, Fiocruz, Minas Gerais, Brazil.
Oscar Bruna-RomeroDepartment of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina, Florianópolis, Brazil.
Pedro Luiz Menin RuizDepartment of Biosciences, Federal University of São Paulo, São Paulo, Brazil.
Daniel Araki RibeiroDepartment of Biosciences, Federal University of São Paulo, São Paulo, Brazil.
Joseli Lannes-VieiraBiology Interactions Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil.
Marcela de Freitas LopesInstitute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Mauricio Martins RodriguesMolecular Immunology Laboratory, Center of Molecular and Cellular Therapy, São Paulo, Brazil.
José Ronnie Carvalho de VasconcelosMolecular Immunology Laboratory, Center of Molecular and Cellular Therapy, São Paulo, Brazil.
Universidade Federal de São Paulo · BRFundação Oswaldo Cruz · BRFundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro · BRUniversidade Federal de Santa Catarina · BR

Funding

Granzyme and Granulysin Mediated Death of Trypanosoma cruziR01AI116577 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI GAZZINELLI, RICARDO TOSTES, LIEBERMAN, JUDY · 2016 to 2020
$3.2M
NIAID NIH HHS R01 AI116577
6 · The paper itself

Abstract

Integrins mediate the lymphocyte migration into an infected tissue, and these cells are essential for controlling the multiplication of many intracellular parasites such as

Indexed as

integrinsmigrationspecific CD8+ T cellsTrypanosoma cruzivaccination

Identifiers

PMID29081775
PMCPMC5645645
OpenAlexW2763873413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.