Evidence map›Paper›PMID 29081724›Full record

ArticleJournal of radiology nursing2017

Role of Stress Cardiac Magnetic Resonance Imaging in Women with Suspected Ischemia but No Obstructive Coronary Artery Disease.

Sawan Jalnapurkar, Parham Zarrini, Puja K Mehta, Louise E J Thomson, Megha Agarwal, Bruce A Samuels, Chrisandra L Shufelt, Jo-Ann Eastwood, Daniel Berman, Noel Bairey Merz and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of radiology nursing, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Stable Ischemic Heart Disease in Women.Current treatment options in cardiovascular medicine · 2018
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Sawan JalnapurkarWomen's Heart Center, Cedars-Sinai Heart Institute, Los Angeles, CA.
Parham ZarriniWomen's Heart Center, Cedars-Sinai Heart Institute, Los Angeles, CA.
Puja K MehtaDivision of Cardiology Emory University School of Medicine.
Louise E J ThomsonS. Mark Taper Foundation Imaging Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Megha AgarwalWomen's Heart Center, Cedars-Sinai Heart Institute, Los Angeles, CA.
Bruce A SamuelsWomen's Heart Center, Cedars-Sinai Heart Institute, Los Angeles, CA.
Chrisandra L ShufeltWomen's Heart Center, Cedars-Sinai Heart Institute, Los Angeles, CA.
Jo-Ann EastwoodWomen's Heart Center, Cedars-Sinai Heart Institute, Los Angeles, CA.
Daniel BermanS. Mark Taper Foundation Imaging Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Noel Bairey MerzWomen's Heart Center, Cedars-Sinai Heart Institute, Los Angeles, CA.
Margo B MinissianWomen's Heart Center, Cedars-Sinai Heart Institute, Los Angeles, CA.
Cedars-Sinai Smidt Heart Institute · USCedars-Sinai Medical Center · USEmory University · USImaging Center · US

Funding

ZONA-FREE HAMSTER OVA ASSAY AS AN INDICATOR OF MALE FERTILITYM01RR000425 · NCRR · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI ANDERSON, GAIL V · 1985 to 2011
$74.2M
Women's Ischemia Syndrome Evaluation (WISE) Coronary Vascular DysfunctionR01HL090957 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI BAIREY MERZ, CATHLEEN NOEL, PEPINE, CARL J · 2008 to 2013
$3.5M
NCRR NIH HHS M01 RR000425NHLBI NIH HHS R01 HL090957
6 · The paper itself

Abstract

objectiveSigns and symptoms of ischemia but no obstructive coronary artery disease (CAD) is often a diagnostic dilemma in women. The use of stress cardiac magnetic resonance imaging (CMRI) for advanced diagnostic assessment in these patients is a non-ionizing radiation option, but the diagnostic utility in this population is unknown. We examined the diagnostic role of stress CMRI in our patient population of these women.

methodsWe analyzed 113 consecutive female patients from 2/2006-11/2007 who had prior cardiac evaluations for signs and symptoms of ischemia but no obstructive CAD who underwent stress CMRI, which included anatomic, functional, adenosine stress perfusion and delayed enhancement imaging.

resultsThe population demographics of 113 women included a mean age of 55±12.2 years with an average body mass index (BMI) of 25 ± 4.5. Overall, 43% had hypertension, 4% had diabetes and 3% were smokers. Overall, 80/113 (70%) demonstrated abnormal stress CMRI results. The majority of patients demonstrated findings consistent with subendocardial perfusion abnormalities suggestive of coronary microvascular dysfunction (CMD). Of note, 3 patients (4%) were diagnosed with congenital coronary anomalies or cardiomyopathy not detected in prior cardiac evaluations.

conclusionAmong women with signs and symptoms of ischemia but no obstructive CAD, stress CMRI is frequently abnormal and is valuable in diagnosis of CMD. Stress CMRI appears useful for advanced diagnostic assessment in these diagnostically challenged patients.

Indexed as

cardiac magnetic resonance imagingcoronary microvascular dysfunctionMyocardial ischemia

Identifiers

PMID29081724
PMCPMC5654630
OpenAlexW2752596349

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.