ArticlePain research & management2017
Physical Activity May Be Associated with Conditioned Pain Modulation in Women but Not Men among Healthy Individuals.
Article in Pain research & management, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 22 citations in OpenAlex.
- High Cardiorespiratory Fitness and Vigorous Physical Activity Relate to Select Pain Sensitivity Assessments in Healthy Adults: A Cross-Sectional Study.Pain research & management · 2026Article
- Associations of pain sensitivity and conditioned pain modulation with physical activity: findings from the Multicenter Osteoarthritis Study (MOST).Osteoarthritis and cartilage · 2024Observational
- The persian version of the fear-avoidance beliefs questionnaire among iranian post-surgery patients: a translation and psychometrics.BMC psychology · 2024Article
- Physical activity, sitting time, and thermal quantitative sensory testing responses in African Americans.Pain reports · 2023Article
- Symptomatic but not Asymptomatic COVID-19 Impairs Conditioned Pain Modulation in Young Adults.The journal of pain · 2022Article
- Influence of self-reported physical activity and sleep quality on conditioned pain modulation in the orofacial region.Clinical oral investigations · 2021Article
- Comparisons of Conditioned Pain Modulation and Physical Activity Between Hispanic and Non-Hispanic White Adults.Journal of racial and ethnic health disparities · 2019Article
- Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundConditioned pain modulation (CPM), a phenomenon also known as diffuse noxious inhibitory control, is thought to be affected by various factors, including sex and level of physical activity. However, the involvement of these factors in CPM remains unclear.
methodsEighty-six healthy young subjects (M/F, 43/43) participated in this study. Participants were assessed on the basis of their mechanical pressure pain threshold (PPT), CPM response, body mass index (BMI), basal metabolic rate (BMR), and duration of moderate-to-vigorous physical activity (MVPA) over a week, using a motion counter. Response to CPM was evaluated as PPT during painful cold stimulation relative to baseline PPT.
resultsMen showed significantly higher baseline PPT than women; however, this difference was no longer significant after controlling for confounders. Stepwise multiple linear regression analyses revealed BMR to be a significant contributor towards baseline PPT in the entire study population. In contrast, although there were no significant contributors to CPM response among men and in the overall study group, MVPA was positively associated with CPM response among women (
conclusionsThese results suggest that, among healthy young individuals, CPM response may be associated with moderate-to-vigorous physical activity in women but not in men.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.