ArticleInternational journal of obesity (2005)2018
Body mass index and infectious disease mortality in midlife in a cohort of 2.3 million adolescents.
Article in International journal of obesity (2005), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Exploring the relationship between life course adiposity and sepsis: insights from a two-sample Mendelian randomization analysis.Frontiers in endocrinology · 2024Pooled it
- Adolescent and Childhood Obesity and Excess Morbidity and Mortality in Young Adulthood-a Systematic Review.Current obesity reports · 2021Pooled it
- Cardiovascular morbidity, diabetes and cancer risk among children and adolescents with severe obesity.Cardiovascular diabetology · 2020Pooled it
- Body mass index and risk of dying from a bloodstream infection: A Mendelian randomization study.PLoS medicine · 2020Trial
- Adult obesity and risk of severe infections: a multicohort study with global burden estimates.Lancet (London, England) · 2026Article
- Feeding the invaders: how metabolic imbalance shapes infection and biofilm development.FEMS microbiology reviews · 2026Review
- High BMI and low cardiorespiratory fitness in adolescence are associated with increased risk of severe bacterial infections in adulthood.Journal of internal medicine · 2026Article
- Adolescent cognitive function and risk of gestational diabetes mellitus: A retrospective population-based cohort study.PloS one · 2026Article
- Association of Modifiable Lifestyle and Metabolic Factors With the Risk of Developing Sepsis: 2-Sample Mendelian Randomized Study.Interactive journal of medical research · 2025Article
- Kidney consequences of obesity.Pediatric nephrology (Berlin, Germany) · 2025Review
- Article
- Body mass index and fitness in late adolescence and risk of cardiovascular disease, respiratory disease, and overall death after COVID-19.Obesity science & practice · 2024Article
- The Bidirectional Association Between Metabolic Syndrome and Long-COVID-19.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Review
- Causal relationships between obesity-related anthropometric indicators and sepsis risk: a Mendelian-randomization study.Frontiers in nutrition · 2024Article
- The Relationship between Body Mass Index and In-Hospital Mortality in Bacteremic Sepsis.Journal of clinical medicine · 2023Article
- Body Mass Index and Antibody Persistence after Measles, Mumps, Rubella and Hepatitis B Vaccinations.Vaccines · 2022Article
- BMI in early adulthood is associated with severe COVID-19 later in life: A prospective cohort study of 1.5 million Swedish men.Obesity (Silver Spring, Md.) · 2022Article
- Diet-induced obesity in mice impairs host defense againstAmerican journal of physiology. Lung cellular and molecular physiology · 2022Article
- Adipocyte inflammation and pathogenesis of viral pneumonias: an overlooked contribution.Mucosal immunology · 2021Review
- Obesity, a major risk factor for immunity and severe outcomes of COVID-19.Bioscience reports · 2021Review
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObesity was linked to altered immunity, but also to favorable outcomes among patients with infectious disease (ID) in some settings. We assessed the association between adolescent body mass index (BMI) and ID mortality.
methodsBMI of 2 294 139 Israeli adolescents (60% men; age 17.4±0.3 years) was measured between 1967 and 2010. The outcome, obtained by linkage with official national records, was death due to ID as the underlying cause. Multivariable Cox proportional hazards models were applied.
resultsDuring 42 297 007 person-years of follow-up (median 18.4 years), there were 689 deaths from ID (mean age 44.1±10.5 years). Adjusted hazard ratios (HR) were 1.039 (1.011-1.068) and 1.146 (1.099-1.194) among men and women, respectively, per unit increment in BMI (P for sex interaction=4.4 × 10
conclusionsAdolescent overweight and obesity were strongly associated with ID mortality, especially of bacterial origin and among women.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.