Evidence map›Paper›PMID 29081329›Full record

Trial reportBehavioural and cognitive psychotherapy2018

Treating Sleep Problems in Young People at Ultra-High Risk of Psychosis: A Feasibility Case Series.

Jonathan Bradley, Daniel Freeman, Eleanor Chadwick, Allison G Harvey, Bradley Mullins, Louise Johns, Bryony Sheaves, Belinda Lennox, Matthew Broome, Felicity Waite

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in Behavioural and cognitive psychotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 3 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 3 syntheses or guidelines pooled it, 75 citations in OpenAlex.

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  13. Synergistic pathways to psychosis: understanding developmental risk and resilience factors.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Jonathan BradleyDepartment of Psychiatry,University of Oxford;Sleep and Circadian Neuroscience Institute,University of Oxford;and Oxford Health NHS Foundation Trust.
Daniel FreemanDepartment of Psychiatry,University of Oxford;Sleep and Circadian Neuroscience Institute,University of Oxford;and Oxford Health NHS Foundation Trust.
Eleanor ChadwickDepartment of Psychiatry,University of Oxford.
Allison G HarveyDepartment of Psychology,UC Berkeley.
Bradley MullinsOxford Health NHS Foundation Trust.
Louise JohnsOxford Health NHS Foundation Trust.
Bryony SheavesDepartment of Psychiatry,University of Oxford;Sleep and Circadian Neuroscience Institute,University of Oxford;and Oxford Health NHS Foundation Trust.ORCID http://orcid.org/0000-0002-2995-193X
Belinda LennoxOxford Health NHS Foundation Trust.
Matthew BroomeDepartment of Psychiatry,University of Oxford;Oxford Health NHS Foundation Trust; and Faculty of Philosophy,University of Oxford.
Felicity WaiteDepartment of Psychiatry,University of Oxford;Sleep and Circadian Neuroscience Institute,University of Oxford;and Oxford Health NHS Foundation Trust.
Oxford Health NHS Foundation Trust · GBBerkeley College · USUniversity of Oxford · GB

Funding

Department of Health RP-2014-05-003Medical Research Council MC_PC_13073Medical Research Council MR/J012939/1Wellcome Trust
6 · The paper itself

Abstract

backgroundOur view is that sleep disturbance may be a contributory causal factor in the development and maintenance of psychotic experiences. A recent series of randomized controlled intervention studies has shown that cognitive-behavioural approaches can improve sleep in people with psychotic experiences. However, the effects of psychological intervention for improving sleep have not been evaluated in young people at ultra-high risk of psychosis. Improving sleep might prevent later transition to a mental health disorder.

aimsTo assess the feasibility and acceptability of an intervention targeting sleep disturbance in young people at ultra-high risk of psychosis.

methodPatients were sought from NHS mental health services. Twelve young people at ultra-high risk of psychosis with sleep problems were offered an eight-session adapted CBT intervention for sleep problems. The core treatment techniques were stimulus control, circadian realignment, and regulating day-time activity. Participants were assessed before and after treatment and at a one month follow-up.

resultsAll eligible patients referred to the study agreed to take part. Eleven patients completed the intervention, and one patient withdrew after two sessions. Of those who completed treatment, the attendance rate was 89% and an average of 7.6 sessions (SD = 0.5) were attended. There were large effect size improvements in sleep. Post-treatment, six patients fell below the recommended cut-off for clinical insomnia. There were also improvements in negative affect and psychotic experiences.

conclusionThis uncontrolled feasibility study indicates that treating sleep problems in young people at ultra-high of psychosis is feasible, acceptable, and may be associated with clinical benefits.

Indexed as

AdolescentCognitive Behavioral TherapyFeasibility StudiesFemaleHumansMalePsychotic DisordersSleep Initiation and Maintenance DisordersSleep Wake DisordersTreatment OutcomeYoung Adultat-risk mental stateinsomniapsychosissleepultra-high risk of psychosis

Identifiers

PMID29081329
PMCPMC5906720
OpenAlexW2765901532

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.