Evidence map›Paper›PMID 29081318›Full record

ArticleInfection control and hospital epidemiology2017

Risk Factors for Healthcare-Associated Infections in Adult Burn Patients.

Paula D Strassle, Felicia N Williams, David J Weber, Emily E Sickbert-Bennett, Anne M Lachiewicz, Sonia Napravnik, Samuel W Jones, Bruce A Cairns, David van Duin

Open access · greenAbstract read
In one paragraph

Article in Infection control and hospital epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 34 citations in OpenAlex.

  1. Trial
  2. Observational
  3. Review
  4. Managing skin infections in burn patients: principles and pitfalls.Current opinion in infectious diseases · 2026
    Review
  5. Review
  6. Article
  7. Evidence Supporting Conservative Scar Management Interventions Following Burn Injury: A Review Article.Journal of burn care & research : official publication of the American Burn Association · 2025
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Evaluation of Burn Wound Infection in a Referral Center in Colombia.Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India · 2022
    Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Paula D Strassle1Department of Epidemiology,University of North Carolina at Chapel Hill,Chapel Hill,North Carolina.
Felicia N Williams2Department of Surgery,University of North Carolina at Chapel Hill,Chapel Hill,North Carolina.
David J Weber1Department of Epidemiology,University of North Carolina at Chapel Hill,Chapel Hill,North Carolina.
Emily E Sickbert-Bennett1Department of Epidemiology,University of North Carolina at Chapel Hill,Chapel Hill,North Carolina.
Anne M Lachiewicz4Division of Infectious Diseases,University of North Carolina,Chapel Hill,North Carolina.
Sonia Napravnik1Department of Epidemiology,University of North Carolina at Chapel Hill,Chapel Hill,North Carolina.
Samuel W Jones2Department of Surgery,University of North Carolina at Chapel Hill,Chapel Hill,North Carolina.
Bruce A Cairns2Department of Surgery,University of North Carolina at Chapel Hill,Chapel Hill,North Carolina.
David van Duin4Division of Infectious Diseases,University of North Carolina,Chapel Hill,North Carolina.
University of North Carolina at Chapel Hill · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
North Carolina Translational & Clinical Sciences Institute (NC TraCS)UL1TR001111 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, CAREY, TIMOTHY S · 2013 to 2017
$43.9M
North Carolina Translational & Clinical Sciences Institute (NC TraCS)KL2TR001109 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, CAREY, TIMOTHY S · 2013 to 2017
$5.7M
Innate Immune Dysfunction Following Burn Inhalation Injury in Humans.K08GM109106 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JONES, SAMUEL WAYNE · 2014 to 2017
$784k
NCATS NIH HHS KL2 TR001109NCATS NIH HHS UL1 TR001111NCATS NIH HHS UL1 TR001863NCATS NIH HHS UL1 TR002489NIGMS NIH HHS K08 GM109106
6 · The paper itself

Abstract

OBJECTIVE Burn patients are particularly vulnerable to infection, and an estimated half of all burn deaths are due to infections. This study explored risk factors for healthcare-associated infections (HAIs) in adult burn patients. DESIGN Retrospective cohort study. SETTING Tertiary-care burn center. PATIENTS Adults (≥18 years old) admitted with burn injury for at least 2 days between 2004 and 2013. METHODS HAIs were determined in real-time by infection preventionists using Centers for Disease Control and Prevention criteria. Multivariable Cox proportional hazards regression was used to estimate the direct effect of each risk factor on time to HAI, with inverse probability of censor weights to address potentially informative censoring. Effect measure modification by burn size was also assessed. RESULTS Overall, 4,426 patients met inclusion criteria, and 349 (7.9%) patients had at least 1 HAI within 60 days of admission. Compared to 6 times as likely to acquire an HAI (HR, 6.38; 95% CI, 3.64-11.17); and patients with >20% TBSA were >10 times as likely to acquire an HAI (HR, 10.33; 95% CI, 5.74-18.60). Patients with inhalational injury were 1.5 times as likely to acquire an HAI (HR, 1.61; 95% CI, 1.17-2.22). The effect of inhalational injury (P=.09) appeared to be larger among patients with ≤20% TBSA. CONCLUSIONS Larger burns and inhalational injury were associated with increased incidence of HAIs. Future research should use these risk factors to identify potential interventions. Infect Control Hosp Epidemiol 2017;38:1441-1448.

Indexed as

AdultAgedBurnsBurn UnitsCross InfectionFemaleHumansIncidenceLength of StayMaleMiddle AgedMultivariate AnalysisNorth CarolinaProportional Hazards ModelsRetrospective StudiesRisk Factors

Identifiers

PMID29081318
PMCPMC5814129
OpenAlexW2765590932

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.