Evidence map›Paper›PMID 29081265›Full record

ReviewChronic respiratory disease2017

Bacterial infections in patients with primary ciliary dyskinesia: Comparison with cystic fibrosis.

Christiaan Dm Wijers, James F Chmiel, Benjamin M Gaston

Open access · goldAbstract readComparative StudyReview
In one paragraph

Review in Chronic respiratory disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 69 citations in OpenAlex.

  1. Microenvironment shapesiScience · 2026
    Article
  2. [Report of 24 cases of primary ciliary dyskinesia in children].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. ERJ open research · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Airway mucus in infection.Frontiers in physiology · 2026
    Review
  11. Article
  12. Advances in Sinonasal Microbiome Analysis.Ear, nose, & throat journal · 2025
    Article
  13. Article
  14. Eosinophilic Pneumonia Triggered byMedicina (Kaunas, Lithuania) · 2024
    Article
  15. Isolation ofERJ open research · 2024
    Article
  16. Article
  17. Article
  18. Antigen stasis and airway nitrosative stress in human primary ciliary dyskinesia.American journal of physiology. Lung cellular and molecular physiology · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Christiaan Dm Wijers1 Department of Pediatrics, Rainbow Babies and Children's Hospital, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
James F Chmiel1 Department of Pediatrics, Rainbow Babies and Children's Hospital, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Benjamin M Gaston1 Department of Pediatrics, Rainbow Babies and Children's Hospital, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Case Western Reserve University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary ciliary dyskinesia (PCD) is an autosomal recessive disorder associated with severely impaired mucociliary clearance caused by defects in ciliary structure and function. Although recurrent bacterial infection of the respiratory tract is one of the major clinical features of this disease, PCD airway microbiology is understudied. Despite the differences in pathophysiology, assumptions about respiratory tract infections in patients with PCD are often extrapolated from cystic fibrosis (CF) airway microbiology. This review aims to summarize the current understanding of bacterial infections in patients with PCD, including infections with Pseudomonas aeruginosa, Staphylococcus aureus, and Moraxella catarrhalis, as it relates to bacterial infections in patients with CF. Further, we will discuss current and potential future treatment strategies aimed at improving the care of patients with PCD suffering from recurring bacterial infections.

Indexed as

Achromobacter denitrificansBacteria, AnaerobicBacterial InfectionsCystic FibrosisHaemophilus influenzaeHumansKartagener SyndromeMoraxella catarrhalisNontuberculous MycobacteriaPseudomonas aeruginosaRalstoniaRespiratory SystemRespiratory Tract InfectionsStaphylococcus aureusStreptococcus pneumoniaeairwaysCFinfectionsmicrobiologyPCD

Identifiers

PMID29081265
PMCPMC5729729
OpenAlexW2591778435

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.