Evidence map›Paper›PMID 29080996›Full record

ArticleEuropean journal of applied physiology2018

Impact of local heating and cooling on skeletal muscle transcriptional response related to myogenesis and proteolysis.

Roksana B Zak, B M Hassenstab, L K Zuehlke, M W S Heesch, R J Shute, T L Laursen, D T LaSalle, D R Slivka

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of applied physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Effect of local cold application during exercise on gene expression related to mitochondrial homeostasis.Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2021
    Article
  9. Article
  10. Effects of 7°C environmental temperature acclimation during a 3-week training period.Journal of applied physiology (Bethesda, Md. : 1985) · 2020
    Article
  11. Article
  12. Article
  13. E-Textiles for Healthy Ageing.Sensors (Basel, Switzerland) · 2019
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Roksana B ZakExercise Physiology Laboratory, School of Health and Kinesiology, University of Nebraska-Omaha, 6001 Dodge Street, Omaha, NE, 68182, USA. rzak@unomaha.edu.ORCID http://orcid.org/0000-0002-9046-5906
B M HassenstabExercise Physiology Laboratory, School of Health and Kinesiology, University of Nebraska-Omaha, 6001 Dodge Street, Omaha, NE, 68182, USA.
L K ZuehlkeExercise Physiology Laboratory, School of Health and Kinesiology, University of Nebraska-Omaha, 6001 Dodge Street, Omaha, NE, 68182, USA.
M W S HeeschExercise Physiology Laboratory, School of Health and Kinesiology, University of Nebraska-Omaha, 6001 Dodge Street, Omaha, NE, 68182, USA.
R J ShuteExercise Physiology Laboratory, School of Health and Kinesiology, University of Nebraska-Omaha, 6001 Dodge Street, Omaha, NE, 68182, USA.
T L LaursenExercise Physiology Laboratory, School of Health and Kinesiology, University of Nebraska-Omaha, 6001 Dodge Street, Omaha, NE, 68182, USA.
D T LaSalleExercise Physiology Laboratory, School of Health and Kinesiology, University of Nebraska-Omaha, 6001 Dodge Street, Omaha, NE, 68182, USA.
D R SlivkaExercise Physiology Laboratory, School of Health and Kinesiology, University of Nebraska-Omaha, 6001 Dodge Street, Omaha, NE, 68182, USA.
University of Nebraska at Omaha · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the impact of local muscle heating and cooling on myogenic and proteolytic gene responses following resistance exercise.

methodsRecreationally trained males (n = 12), age 25.3 ± 1.5, % body fat 13.6 ± 1.92, completed four sets of 8-12 repetitions of unilateral leg press and leg extension while heating one leg, and cooling the other. Muscle biopsies were taken from the vastus lateralis of each leg pre and 4 h post exercise.

resultsMyoD, FOXO1, and MuRF1 mRNA increased with exercise regardless of temperature (p < 0.05). Myostatin, MYF5, and atrogin-1 mRNA decreased with exercise regardless of temperature (p < 0.05). Myogenin, MRF4, and CASP3 mRNA were higher in the hot condition, compared to the cold (p < 0.05). PAX7 mRNA was lower in the hot compared to cold condition (p = 0.041). FOXO3 mRNA was higher in the cold compared to hot condition (p = 0.037). AKT1 and AKT2 were unaffected by either exercise or temperature. Femoral artery blood flow volume was higher in the hot (375.2 ± 41.2 ml min

conclusionThese results suggest an impaired muscle growth response with local cold application compared to local heat application.

Indexed as

Hyperthermia, InducedHypothermia, InducedMuscle DevelopmentProteolysisAdultHumansMaleMuscle ProteinsMuscle, SkeletalRandom AllocationResistance TrainingRNA, MessengerMuscle ProteinsRNA, MessengerColdHotMuscle breakdownMuscle growthResistance exerciseTemperature

Identifiers

PMID29080996
OpenAlexW2766785457

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.