Evidence map›Paper›PMID 29080959›Full record

SynthesisTechniques in coloproctology2017

Short-term efficacy and safety of three novel sphincter-sparing techniques for anal fistulae: a systematic review.

S O Adegbola, K Sahnan, G Pellino, P J Tozer, A Hart, R K S Phillips, J Warusavitarne, O D Faiz

Registry-linked trialAbstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Techniques in coloproctology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03861689 (A Prospective Longitudinal Study on the Effect of Tight Control Management on Perianal Crohn's Disease), which is not on this map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03861689 naunknown statusnot on this mapstarted 2019, after this paper: background citation

A Prospective Longitudinal Study on the Effect of Tight Control Management on Perianal Crohn's Disease

TypeinterventionalSponsorChinese University of Hong KongRan2019 to 2024Enrolled40ConditionsInflammatory Bowel Diseases, Perianal FistulaArmsMRI pelvis
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Article
  5. Article
  6. Observational
  7. Article
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  10. Review
  11. Article
  12. Article
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  14. Review
  15. Review
  16. Article
  17. Observational
  18. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

S O AdegbolaFistula Research Unit, St Mark's Hospital and Academic Institute, Harrow, UK. samadeg@doctors.net.uk.
K SahnanFistula Research Unit, St Mark's Hospital and Academic Institute, Harrow, UK.
G PellinoFistula Research Unit, St Mark's Hospital and Academic Institute, Harrow, UK.
P J TozerFistula Research Unit, St Mark's Hospital and Academic Institute, Harrow, UK.
A HartFistula Research Unit, St Mark's Hospital and Academic Institute, Harrow, UK.
R K S PhillipsFistula Research Unit, St Mark's Hospital and Academic Institute, Harrow, UK.
J WarusavitarneFistula Research Unit, St Mark's Hospital and Academic Institute, Harrow, UK.
O D FaizFistula Research Unit, St Mark's Hospital and Academic Institute, Harrow, UK.
Imperial College London · GBSt Mark's Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe surgical treatment of complex anal fistulae, particularly those involving a significant portion of the anal sphincter in which fistulotomy would compromise continence, is challenging. Video-assisted anal fistula treatment (VAAFT), fistula tract laser closure (FiLaC™) and over-the-scope clip (OTSC

methodsA systematic search of major databases was performed using defined terms. All studies reporting on experience of these techniques were included and outcomes (fistula healing and safety) evaluated.

resultsEighteen studies (VAAFT-12, FiLaC™-3, OTSC

conclusionsAll three techniques appear to be safe and feasible options in the management of anal fistulae, and short-term healing rates are acceptable with no sustained effect on continence. There is, however, a paucity of robust data with long-term outcomes. These techniques are thus welcome additions; however, their long-term place in the colorectal surgeon's armamentarium, whether diagnostic or therapeutic, remains uncertain.

Indexed as

Laser TherapyVideo-Assisted SurgeryAnal CanalHumansOperative TimeOrgan Sparing TreatmentsProctoscopyRectal FistulaAnal fistulaFistula tract laser closureOver-the-scope clipVAAFTVideo-assisted anal fistula treatment

Identifiers

PMID29080959
OpenAlexW2765287013

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.