ArticleTechniques in coloproctology2017
Validation of an online risk calculator for the prediction of anastomotic leak after colon cancer surgery and preliminary exploration of artificial intelligence-based analytics.
Article in Techniques in coloproctology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Artificial intelligence in colorectal surgery: an AI-powered systematic review.Techniques in coloproctology · 2023Pooled it
- Systematic review of preoperative and intraoperative colorectal Anastomotic Leak Prediction Scores (ALPS).BMJ open · 2023Pooled it
- AI Trustworthiness in the Perioperative Period for Patients with Serious Illness: Scoping Narrative Review.JMIR perioperative medicine · 2026Article
- Prevention and management of anastomotic leakage after colorectal resection: evolving trends among Italian surgeons. A SICCR survey.Updates in surgery · 2026Article
- Review
- Automatic surgical skill assessment using a task classification model in laparoscopic sigmoidectomy.Surgical endoscopy · 2025Article
- A Novel Deep Learning Model for Predicting Colorectal Anastomotic Leakage: A Pioneer Multicenter Transatlantic Study.Journal of clinical medicine · 2025Article
- Early detection of colonic anastomotic leak.ANZ journal of surgery · 2025Article
- Machine learning and deep learning to improve prevention of anastomotic leak after rectal cancer surgery.World journal of gastrointestinal surgery · 2025Article
- Artificial Intelligence in Surgery: A Systematic Review of Use and Validation.Journal of clinical medicine · 2024Review
- Predictive Factors for Anastomotic Leakage Following Colorectal Cancer Surgery: Where Are We and Where Are We Going?Current oncology (Toronto, Ont.) · 2023Review
- Training prediction models for individual risk assessment of postoperative complications after surgery for colorectal cancer.Techniques in coloproctology · 2022Article
- Differential Performance of Machine Learning Models in Prediction of Procedure-Specific Outcomes.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022Article
- Risk Nomogram Does Not Predict Anastomotic Leakage After Colon Surgery Accurately: Results of the Multi-center LekCheck Study.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022Article
- Laparoscopic resection and primary anastomosis for perforated diverticulitis: with or without loop ileostomy? The response is the colon leakage risk score!Updates in surgery · 2022Article
- Italian multi-society modified Delphi consensus on the definition and management of anastomotic leakage in colorectal surgery.Updates in surgery · 2020Article
- Evaluating the ACS-NSQIP Risk Calculator in Primary GI Neuroendocrine Tumor: Results from the United States Neuroendocrine Tumor Study Group.The American surgeon · 2019Article
- Modified Colon Leakage Score to Predict Anastomotic Leakage in Patients Who Underwent Left-Sided Colorectal Surgery.Journal of clinical medicine · 2019Article
- The REAL (REctal Anastomotic Leak) score for prediction of anastomotic leak after rectal cancer surgery.Techniques in coloproctology · 2019Article
- Laparoscopic versus open colectomy: the impact of frailty on outcomes.Updates in surgery · 2019Article
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Authors and funding
8 authors.
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Abstract
backgroundRecently published data support the use of a web-based risk calculator ( www.anastomoticleak.com ) for the prediction of anastomotic leak after colectomy. The aim of this study was to externally validate this calculator on a larger dataset.
methodsConsecutive adult patients undergoing elective or emergency colectomy for colon cancer at a single institution over a 9-year period were identified using the Binational Colorectal Cancer Audit database. Patients with a rectosigmoid cancer, an R2 resection, or a diverting ostomy were excluded. The primary outcome was anastomotic leak within 90 days as defined by previously published criteria. Area under receiver operating characteristic curve (AUROC) was derived and compared with that of the American College of Surgeons National Surgical Quality Improvement Program
resultsA total of 626 patients were identified. Four hundred and fifty-six patients met the inclusion criteria, and 402 had complete data available for all the calculator variables (126 had a left colectomy). Laparoscopic surgery was performed in 39.6% and emergency surgery in 14.7%. The anastomotic leak rate was 7.2%, with 31.0% requiring reoperation. The anastomoticleak.com calculator was significantly predictive of leak and performed better than the ACS NSQIP calculator (AUROC 0.73 vs 0.58) and the CLS calculator (AUROC 0.96 vs 0.80) for left colectomy. Artificial intelligence-predictive analysis supported these findings and identified an improved prediction model.
conclusionsThe anastomotic leak risk calculator is significantly predictive of anastomotic leak after colon cancer resection. Wider investigation of artificial intelligence-based analytics for risk prediction is warranted.
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