Evidence map›Paper›PMID 29080638›Full record

ReviewEndocrinology and metabolism clinics of North America2017

Biology and Mechanisms of Action of the Vitamin D Hormone.

J Wesley Pike, Sylvia Christakos

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Endocrinology and metabolism clinics of North America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 157 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
157citing papers in PubMed, 9 pooled it
14.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

157 citing papers in PubMed, 9 syntheses or guidelines pooled it, 280 citations in OpenAlex.

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  18. Identification and Association ofCurrent issues in molecular biology · 2025
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97 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

J Wesley PikeDepartment of Biochemistry, University of Wisconsin-Madison, Biochem Addition, Room 543D, 433 Babcock Drive, Madison, WI 53706, USA. Electronic address: pike@biochem.wisc.edu.
Sylvia ChristakosDepartment of Microbiology, Biochemistry and Molecular Genetics, Rutgers, The State University of New Jersey, New Jersey Medical School, 185 South Orange Avenue, Newark, NJ 07103, USA.
Rutgers, The State University of New Jersey · USUniversity of Wisconsin–Madison · US

Funding

BONE CELL REGULATION OF THE VITAMIN D RECEPTOR GENER01AR045173 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI PIKE, J WESLEY · 1999 to 2015
$3.5M
Dynamic Mechanisms of Vitamin D-Induced Gene ExpressionR01DK072281 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI PIKE, J WESLEY · 2005 to 2012
$2.6M
Integrative genomics to define osteocyte differentiation, regulation and functionR01AR064424 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI PIKE, J WESLEY · 2014 to 2018
$1.7M
NIAMS NIH HHS R01 AR045173NIAMS NIH HHS R01 AR064424NIDDK NIH HHS R01 DK072281
6 · The paper itself

Abstract

The central role of hormonal 1,25-dihydroxyvitamin D

Indexed as

AnimalsBone and BonesCalcitriolCalciumHomeostasisHumansReceptors, CalcitriolSignal TransductionVitamin DCalcitriolCalciumReceptors, CalcitriolVitamin DCalcemic hormonesGenetic linkageGenome-wide principlesMineral homeostasisRANKLTarget genesTranscriptionTransient receptor potential vanilloid type-6 (TRPV6)

Identifiers

PMID29080638
PMCPMC5762112
OpenAlexW2759805322

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.