ReviewCurrent opinion in structural biology2018
Protein folding transition path times from single molecule FRET.
Review in Current opinion in structural biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
56 citing papers in PubMed, 122 citations in OpenAlex.
- Fast sampling of protein conformational dynamics.Science advances · 2026Article
- Cooperative Native Contact Formation Facilitates Free Energy Barrier Crossing in Protein Folding.Physical review letters · 2026Article
- Dynamic control of IDP interaction network via diverse binding pathways.Nature communications · 2026Article
- Hierarchical friction memory leads to subdiffusive configurational dynamics of fast-folding proteins.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Development of three-colour FRET cascade for force sensing of the putative RIAM-vinculin interaction in fibroblasts.Communications chemistry · 2025Article
- Three-color single-molecule maximum likelihood analysis of folding and binding of diffusing molecules.Biophysical journal · 2025Article
- Quantitative analysis methods for free diffusion single-molecule FRET experiments.Current opinion in structural biology · 2025Review
- Particle dynamics in biconical cavities: First-passage, direct-transit, and looping time distributions.The Journal of chemical physics · 2025Article
- The significance of fuzzy boundaries of the barrier regions in single-molecule measurements of failed barrier crossing attempts.The Journal of chemical physics · 2024Article
- Hydrogen bonding heterogeneity correlates with protein folding transition state passage time as revealed by data sonification.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Article
- Milestoning estimators of dissipation in systems observed at a coarse resolution.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Folding speeds of helical membrane proteins.Biochemical Society transactions · 2024Review
- Energy landscape of conformational changes for a single unmodified protein.Npj biosensing · 2024Article
- Counter-Intuitive Features of Particle Dynamics in Nanopores.International journal of molecular sciences · 2023Review
- Features of Protein Unfolding Transitions and Their Relation to Domain Topology Probed by Single-Molecule FRET.Biomolecules · 2023Article
- Protein folding rate evolution upon mutations.Biophysical reviews · 2023Review
- Analysis of photon trajectories from diffusing single molecules.The Journal of chemical physics · 2023Article
- Robust membrane protein tweezers reveal the folding speed limit of helical membrane proteins.eLife · 2023Article
- Machine Learning Generation of Dynamic Protein Conformational Ensembles.Molecules (Basel, Switzerland) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
The transition path is the tiny segment of a single molecule trajectory when the free energy barrier between states is crossed and for protein folding contains all of the information about the self-assembly mechanism. As a first step toward obtaining structural information during the transition path from experiments, single molecule FRET spectroscopy has been used to determine average transition path times from a photon-by-photon analysis of fluorescence trajectories. These results, obtained for several different proteins, have already provided new and demanding tests that support both the accuracy of all-atom molecular dynamics simulations and the basic postulates of energy landscape theory of protein folding.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.