Evidence map›Paper›PMID 29080063›Full record

ArticleInternational ophthalmology2018

Validity of a new comprehensive pterygia grading scale for use in clinical research and clinical trial.

Ping Huang, Jianyan Huang, Tudor Tepelus, Jyotsna Maram, Srinivas Sadda, Olivia L Lee

Abstract readValidation Study
PubMed Publisher
In one paragraph

Article in International ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Computer-Assisted Pterygium Screening System: A Review.Diagnostics (Basel, Switzerland) · 2022
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ping HuangDoheny Image Reading Center, Doheny Eye Institute, Los Angeles, CA, USA.
Jianyan HuangDoheny Image Reading Center, Doheny Eye Institute, Los Angeles, CA, USA.
Tudor TepelusDoheny Image Reading Center, Doheny Eye Institute, Los Angeles, CA, USA.
Jyotsna MaramDoheny Image Reading Center, Doheny Eye Institute, Los Angeles, CA, USA.
Srinivas SaddaDoheny Image Reading Center, Doheny Eye Institute, Los Angeles, CA, USA.
Olivia L LeeDoheny Image Reading Center, Doheny Eye Institute, Los Angeles, CA, USA. olee@doheny.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the reliability and agreement of a new comprehensive pterygium grading scale for use in clinical research and clinical trials.

methodsThirty eyes with pterygia were enrolled in this study. Primary gaze position and lateral gaze position images were taken of each eye with a modified single-lens reflex camera system. Our grading scale includes five parameters: two hyperemia parameters of pterygia on two different gaze position images and three size parameters, quantifying length, width, and area of the cornea encroachment of pterygium, using ImageJ software. All images were graded on the five parameters by two masked, certified reading center graders. Two graders independently graded all the images to determine inter-grader reliability. One grader regraded the images after 3 days to determine intra-grader reliability. Intraclass correlation coefficient (ICC) and inter-rater agreement statistic (κ) calculations were performed.

resultsThe intra-grader reliability for hyperemia grading was high on both primary and lateral gazing positions (κ value is 0.93 and 0.96). The inter-grader reliability for hyperemia grading was also good (κ value is 0.85 and 0.87). The mean value of width, length, and area of the cornea encroachment of pterygium was 4.31 ± 2.04 mm, 2.08 ± 1.43 mm, and 7.84 ± 7.62 mm

conclusionsThere was excellent intra- and inter-observer reproducibility with the new comprehensive grading scale. This scale could lead to the development of standardized grading assessments and quantification of pterygia that would be valid in clinical research and clinical trials.

Indexed as

Biomedical ResearchClinical Trials as TopicAdultDiagnostic Techniques, OphthalmologicalFemaleHumansMaleMiddle AgedObserver VariationPhotographyPterygiumReproducibility of ResultsGrading scaleImagePterygium

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.