Evidence map›Paper›PMID 29080017›Full record

ArticleEJNMMI research2017

Safety, pharmacokinetics, metabolism and radiation dosimetry of

Huailei Jiang, Nicholas R Schmit, Alex R Koenen, Aditya Bansal, Mukesh K Pandey, Robert B Glynn, Bradley J Kemp, Kera L Delaney, Angela Dispenzieri, Jamie N Bakkum-Gamez and 5 more

Abstract read
In one paragraph

Article in EJNMMI research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Trial
  2. Diagnostic performance of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  3. Review
  4. [Future oncology (London, England) · 2025
    Article
  5. Recent developments in translational imaging of in vivo gene therapy outcomes.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  6. Gene editing enables non-invasiveMolecular therapy. Methods & clinical development · 2025
    Article
  7. Review
  8. [EJNMMI research · 2024
    Article
  9. Endocrinology application of molecular imaging: current role of PET/CT.Journal of endocrinological investigation · 2024
    Review
  10. Review
  11. Diagnostic Performance of [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Article
  12. High molar activity [EJNMMI radiopharmacy and chemistry · 2022
    Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021
    Article
  20. The chemical tool-kit for molecular imaging with radionuclides in the age of targeted and immune therapy.Cancer imaging : the official publication of the International Cancer Imaging Society · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Huailei JiangDepartment of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
Nicholas R SchmitDepartment of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
Alex R KoenenDepartment of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
Aditya BansalDepartment of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
Mukesh K PandeyDepartment of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
Robert B GlynnDepartment of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
Bradley J KempDepartment of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
Kera L DelaneyDepartment of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
Angela DispenzieriDepartment of Medicine, Mayo Clinic, Rochester, MN, USA.
Jamie N Bakkum-GamezDepartment of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN, USA.
Kah-Whye PengDepartment of Molecular Medicine, Mayo Clinic, Rochester, MN, USA.
Stephen J RussellDepartment of Molecular Medicine, Mayo Clinic, Rochester, MN, USA.
Tina M GundersonDepartment of Clinical Statistics, Mayo Clinic, Rochester, MN, USA.
Val J LoweDepartment of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
Timothy R DeGradoDepartment of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA. degrado.timothy@mayo.edu.ORCID http://orcid.org/0000-0002-0511-5398

Funding

First in-human PET imaging studies of NIS reporter [18F]BF4R01CA196975 · NCI · MAYO CLINIC ROCHESTER · PI DEGRADO, TIMOTHY R. · 2016 to 2018
$518k
NCI NIH HHS R01 CA196975
6 · The paper itself

Abstract

background

methods

results

conclusionsThis initial study in healthy human subjects showed

Indexed as

18F-fluorineBiodistributionDosimetryPET imagingSodium/iodide symporterTetrafluoroborate

Identifiers

PMID29080017
PMCPMC5660009

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.