Evidence map›Paper›PMID 29079838›Full record

ArticleScientific reports2017

Yeast diversity in relation to the production of fuels and chemicals.

Jia Wu, Adam Elliston, Gwenaelle Le Gall, Ian J Colquhoun, Samuel R A Collins, Jo Dicks, Ian N Roberts, Keith W Waldron

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Synthesis of ethyl acetate from glucose byEngineering in life sciences · 2021
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jia WuThe Biorefinery Centre, Quadram Institute Bioscience, Norwich Research Park, Colney, Norwich, NR4 7UA, UK.
Adam EllistonThe Biorefinery Centre, Quadram Institute Bioscience, Norwich Research Park, Colney, Norwich, NR4 7UA, UK.
Gwenaelle Le GallThe Analytical Sciences Unit, Quadram Institute Bioscience, Norwich Research Park, Colney, Norwich, NR4 7UA, UK.
Ian J ColquhounThe Analytical Sciences Unit, Quadram Institute Bioscience, Norwich Research Park, Colney, Norwich, NR4 7UA, UK.
Samuel R A CollinsThe Biorefinery Centre, Quadram Institute Bioscience, Norwich Research Park, Colney, Norwich, NR4 7UA, UK.
Jo DicksThe National Collection of Yeast Cultures, Quadram Institute Bioscience, Norwich Research Park, Colney, Norwich, NR4 7UA, UK.
Ian N RobertsThe National Collection of Yeast Cultures, Quadram Institute Bioscience, Norwich Research Park, Colney, Norwich, NR4 7UA, UK.
Keith W WaldronThe Biorefinery Centre, Quadram Institute Bioscience, Norwich Research Park, Colney, Norwich, NR4 7UA, UK. keith.waldron@quadram.ac.uk.
Quadram Institute · GBNorwich Research Park · GB

Funding

Biotechnology and Biological Sciences Research Council BB/J004545/1Biotechnology and Biological Sciences Research Council BB/J013838/1
6 · The paper itself

Abstract

In addition to ethanol, yeasts have the potential to produce many other industrially-relevant chemicals from numerous different carbon sources. However there remains a paucity of information about overall capability across the yeast family tree. Here, 11 diverse species of yeasts with genetic backgrounds representative of different branches of the family tree were investigated. They were compared for their abilities to grow on a range of sugar carbon sources, to produce potential platform chemicals from such substrates and to ferment hydrothermally pretreated rice straw under simultaneous saccharification and fermentation conditions. The yeasts differed considerably in their metabolic capabilities and production of ethanol. A number could produce significant amounts of ethyl acetate, arabinitol, glycerol and acetate in addition to ethanol, including from hitherto unreported carbon sources. They also demonstrated widely differing efficiencies in the fermentation of sugars derived from pre-treated rice straw biomass and differential sensitivities to fermentation inhibitors. A new catabolic property of Rhodotorula mucilaginosa (NCYC 65) was discovered in which sugar substrate is cleaved but the products are not metabolised. We propose that engineering this and some of the other properties discovered in this study and transferring such properties to conventional industrial yeast strains could greatly expand their biotechnological utility.

Indexed as

BiodiversityBiofuelsCarbonFermentationOryzaRhodotorulaSpecies SpecificitySugarsBiofuelsCarbonSugars

Identifiers

PMID29079838
PMCPMC5660169
OpenAlexW2765746097

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.