ArticleGenome research2017
Deep sequencing of natural and experimental populations of
Article in Genome research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
32 citing papers in PubMed.
- Estimating the evolutionary fitness of specific synonymous codon changes.Molecular biology and evolution · 2026Article
- Estimating the evolutionary fitness of specific synonymous codon changes.bioRxiv : the preprint server for biology · 2026Article
- Highly Recurrent Multinucleotide Mutations in SARS-CoV-2.Molecular biology and evolution · 2025Article
- The mutation landscape ofbioRxiv : the preprint server for biology · 2025Article
- A gene-based model of fitness and its implications for genetic variation: Genetic and inbreeding loads.bioRxiv : the preprint server for biology · 2025Article
- Genome-wide impact of codon usage bias on translation optimization in Drosophila melanogaster.Nature communications · 2024Article
- Low-input PacBio sequencing generates high-quality individual fly genomes and characterizes mutational processes.Nature communications · 2024Article
- Germline mutation rate is elevated in young and old parents inEvolution letters · 2023Article
- Article
- Evolutionary Shortcuts via Multinucleotide Substitutions and Their Impact on Natural Selection Analyses.Molecular biology and evolution · 2023Article
- Recent Evolution of a Maternally Acting Sex-Determining Supergene in a Fly with Single-Sex Broods.Molecular biology and evolution · 2023Article
- Variation in mutation, recombination, and transposition rates inGenome research · 2023Article
- How Can We Resolve Lewontin's Paradox?Genome biology and evolution · 2022Article
- Article
- Pairs of Mutually Compensatory Frameshifting Mutations Contribute to Protein Evolution.Molecular biology and evolution · 2022Article
- Drosophila Evolution over Space and Time (DEST): A New Population Genomics Resource.Molecular biology and evolution · 2021Article
- Genome-wide oscillations in G + C density and sequence conservation.Genome research · 2021Article
- Evidence for a force favoring GC over AT at short intronic sites in Drosophila simulans and Drosophila melanogaster.G3 (Bethesda, Md.) · 2021Article
- Locally Adaptive Inversions Modulate Genetic Variation at Different Geographic Scales in a Seaweed Fly.Molecular biology and evolution · 2021Article
- Pedigree-based and phylogenetic methods support surprising patterns of mutation rate and spectrum in the gray mouse lemur.Heredity · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Mutations provide the raw material of evolution, and thus our ability to study evolution depends fundamentally on having precise measurements of mutational rates and patterns. We generate a data set for this purpose using (1) de novo mutations from mutation accumulation experiments and (2) extremely rare polymorphisms from natural populations. The first, mutation accumulation (MA) lines are the product of maintaining flies in tiny populations for many generations, therefore rendering natural selection ineffective and allowing new mutations to accrue in the genome. The second, rare genetic variation from natural populations allows the study of mutation because extremely rare polymorphisms are relatively unaffected by the filter of natural selection. We use both methods in
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.