Evidence map›Paper›PMID 29079628›Full record

ArticleApplied and environmental microbiology2018

Neutralizing Anti-Heat-Stable Toxin (STa) Antibodies Derived from Enterotoxigenic Escherichia coli Toxoid Fusions with STa Proteins Containing N12S, L9A/N12S, or N12S/A14T Mutations Show Little Cross-Reactivity with Guanylin or Uroguanylin.

Qiangde Duan, Jiachen Huang, Nan Xiao, Hyesuk Seo, Weiping Zhang

Open access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Recent progress in enterotoxigenicInfection and immunity · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Adjuvant effect of enterotoxigenicHuman vaccines & immunotherapeutics · 2020
    Article
  11. Article
  12. Review
  13. Development of an enterotoxigenicHuman vaccines & immunotherapeutics · 2019
    Review
  14. Article
  15. Co-administered Tag-Less Toxoid Fusion 3xSTaFrontiers in microbiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Qiangde DuanDepartment of Diagnostic Medicine/Pathobiology, Kansas State University College of Veterinary Medicine, Manhattan, Kansas, USA.
Jiachen HuangDepartment of Diagnostic Medicine/Pathobiology, Kansas State University College of Veterinary Medicine, Manhattan, Kansas, USA.
Nan XiaoDepartment of Diagnostic Medicine/Pathobiology, Kansas State University College of Veterinary Medicine, Manhattan, Kansas, USA.
Hyesuk SeoDepartment of Diagnostic Medicine/Pathobiology, Kansas State University College of Veterinary Medicine, Manhattan, Kansas, USA.
Weiping ZhangDepartment of Diagnostic Medicine/Pathobiology, Kansas State University College of Veterinary Medicine, Manhattan, Kansas, USA wpzhang@vet.k-state.edu.ORCID http://orcid.org/0000-0002-3723-2257
Kansas State University · US

Funding

A broadly protective subunit vaccine against enterotoxigenic Escherichia coli (ETEC) associateddiarrheaR01AI121067 · NIAID · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI ZHANG, WEIPING · 2016 to 2020
$2.0M
NIAID NIH HHS R01 AI121067
6 · The paper itself

Abstract

Heat-stable toxin (STa)-producing enterotoxigenic

Indexed as

AnimalsAntibodies, BacterialAntibodies, NeutralizingAntigens, BacterialBacterial ToxinsChildCross ReactionsEnterotoxigenic Escherichia coliEnterotoxinsEscherichia coli InfectionsFemaleGastrointestinal HormonesHot TemperatureHumansImmunizationMiceAntibodies, BacterialAntibodies, NeutralizingAntigens, BacterialBacterial ToxinsEnterotoxinsGastrointestinal HormonesguanylinNatriuretic PeptidesToxoidsuroguanylinantibody cross-reactivitydiarrheaenterotoxigenic Escherichia coliETECguanylinuroguanylin

Identifiers

PMID29079628
PMCPMC5752861
OpenAlexW2766445115

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.