Evidence map›Paper›PMID 29079600›Full record

Trial reportHaematologica2018

Treatment of essential thrombocythemia in Europe: a prospective long-term observational study of 3649 high-risk patients in the Evaluation of Anagrelide Efficacy and Long-term Safety study.

Gunnar Birgegård, Carlos Besses, Martin Griesshammer, Luigi Gugliotta, Claire N Harrison, Mohamed Hamdani, Jingyang Wu, Heinrich Achenbach, Jean-Jacques Kiladjian

Open access · goldAbstract readClinical Trial, Phase IVMulticenter StudyObservational Study
In one paragraph

Trial report in Haematologica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Observational
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 7 countries.

Gunnar BirgegårdDepartment of Haematology, Institute for Medical Sciences, Uppsala University, Sweden gunnar.birgegard@medsci.uu.se.
Carlos BessesDepartment of Hematology, Hospital del Mar-IMIM, Barcelona, Spain.
Martin GriesshammerHematology and Oncology, Johannes Wesling Medical Center, Minden, Germany.
Luigi GugliottaDepartment of Haematology, 'L e A Seragnoli', Sant'Orsola-Malpighi Hospital, Bologna, Italy.
Claire N HarrisonDepartment of Haematology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Mohamed HamdaniGlobal Biometrics, Shire Pharmaceuticals, Lexington, MA, USA.
Jingyang WuGlobal Biometrics, Shire Pharmaceuticals, Lexington, MA, USA.
Heinrich AchenbachResearch & Development, Shire GmbH, Zug, Switzerland.
Jean-Jacques KiladjianAPHP, Hopital Saint-Louis, Paris, France.
Takeda (United States) · USAssistance Publique – Hôpitaux de Paris · FRGuy's and St Thomas' NHS Foundation Trust · GBHospital Del Mar · ESJohannes Wesling Klinikum Minden · DEPoliclinico S.Orsola-Malpighi · ITUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evaluation of Anagrelide (Xagrid

Indexed as

AdolescentAdultAgedAged, 80 and overBiomarkersCell Transformation, NeoplasticDisease ManagementDisease ProgressionEuropeFemaleHumansMaleMiddle AgedMortalityPregnancyPregnancy Complications, HematologicanagrelideBiomarkersQuinazolines

Identifiers

PMID29079600
PMCPMC5777190
OpenAlexW2765738369

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.