Evidence map›Paper›PMID 29079485›Full record

ArticleMethods (San Diego, Calif.)2018

Single-shot dual-wavelength interferometric microscopy.

Poorya Hosseini, Di Jin, Zahid Yaqoob, Peter T C So

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Methods (San Diego, Calif.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 12 citations in OpenAlex.

  1. Quantitative phase microscopies: accuracy comparison.Light, science & applications · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Poorya HosseiniDepartment of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States; Laser Biomedical Research Center, Massachusetts Institute of Technology, Cambridge, MA 02139, United States. Electronic address: prossini@mit.edu.
Di JinDepartment of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States; Laser Biomedical Research Center, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.
Zahid YaqoobLaser Biomedical Research Center, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.
Peter T C SoDepartment of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States; Laser Biomedical Research Center, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.
Massachusetts Institute of Technology · US

Funding

Wide-Field Short-Wave Infrared (SWIR) multiphoton (MP) tissue imagingP41EB015871 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SO, PETER T. · 2012 to 2021
$11.3M
In Vivo Imaging of Neuronal Plasticity in Visual CortexR01EY017656 · NEI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI NEDIVI, ELLY, SO, PETER T. · 2008 to 2014
$2.5M
Characterizing mechanisms of sickle cell crisis via dynamic optical assayR01HL121386 · NHLBI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SO, PETER T. · 2014 to 2016
$1.7M
Regenerative Healing Using ECM Based ScaffoldsR01NS051320 · NINDS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI YANNAS, IOANNIS V · 2006 to 2009
$1.6M
High Throughput Manufacturing for Three-Dimensional Microfluidic DevicesR44EB012415 · NIBIB · FEMTOFAB, INC. · PI JANG, YUN-HO · 2011 to 2013
$849k
NEI NIH HHS R01 EY017656NHLBI NIH HHS R01 HL121386NIBIB NIH HHS P41 EB015871NIBIB NIH HHS R44 EB012415NINDS NIH HHS R01 NS051320
6 · The paper itself

Abstract

Interferometric microscopy (IM) can provide complex field information of the biological samples with high spatial and temporal resolution with virtually no photodamage. Measuring wavelength-dependent information in particular has a wide range of applications from cell and tissue refractometry to the cellular biophysical measurements. IM measurements at multiple wavelengths are typically associated with a loss in temporal resolution, field of view, stability, sensitivity, and may involve using expensive equipment such as tunable filters or spatial light modulators. Here, we present a novel and simple design for an interferometric microscope that provides single-shot off-axis interferometric measurements at two wavelengths by encoding the two spectral images at two orthogonal spatial frequencies that allows clean separation of information in the Fourier space with no resolution loss. We demonstrated accurate simultaneous quantification of polystyrene bead refractive indices at two wavelengths.

Indexed as

Equipment DesignImage EnhancementLightMicroscopy, InterferenceRefractometryCellular imagingDispersionInterferometric microscopyLabel-free imagingQuantitative phase

Identifiers

PMID29079485
PMCPMC5857408
OpenAlexW2766911262

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.