Evidence map›Paper›PMID 29079333›Full record

ArticleAnnals of epidemiology2017

Childhood physical and sexual abuse experiences associated with post-traumatic stress disorder among pregnant women.

Sixto E Sanchez, Omar Pineda, Diana Z Chaves, Qiu-Yue Zhong, Bizu Gelaye, Gregory E Simon, Marta B Rondon, Michelle A Williams

Open access · greenAbstract readComparative Study
In one paragraph

Article in Annals of epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Global mental health (Cambridge, England) · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Polygenic prediction and GWAS of depression, PTSD, and suicidal ideation/self-harm in a Peruvian cohort.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020
    Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Sixto E SanchezAsociación Civil PROESA, Lima, Peru; Universidad Peruana de Ciencias Aplicados, Lima, Peru.
Omar PinedaMultidisciplinary International Research Training, Harvard T. H. Chan School of Public Health, Boston, MA.
Diana Z ChavesMultidisciplinary International Research Training, Harvard T. H. Chan School of Public Health, Boston, MA.
Qiu-Yue ZhongDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA.
Bizu GelayeDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA. Electronic address: bgelaye@hsph.harvard.edu.
Gregory E SimonGroup Health Research Institute, Seattle, WA.
Marta B RondonDepartment of Medicine, Cayetano Heredia Peruvian University, Lima, Peru.
Michelle A WilliamsDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA.
Harvard University · USKaiser Permanente Washington Health Research Institute · USPeruvian University of Applied Sciences · PEUniversidad Peruana Cayetano Heredia · PE

Funding

University of Washington MHIRT Training Program GrantT37MD001449 · NIMHD · UNIVERSITY OF WASHINGTON · PI WILLIAMS, MICHELLE A. · 2005 to 2018
$3.5M
A Cohort Study of Preterm Delivery in Relation to Partner Abuse, Mood and AnxietyR01HD059835 · NICHD · UNIVERSITY OF WASHINGTON · PI WILLIAMS, MICHELLE A. · 2010 to 2014
$2.8M
NICHD NIH HHS R01 HD059835NIMHD NIH HHS T37 MD001449
6 · The paper itself

Abstract

purposeWe sought to evaluate the extent to which childhood physical and/or sexual abuse history is associated with post-traumatic stress disorder (PTSD) during early pregnancy and to explore the extent to which the childhood abuse-PTSD association is mediated through, or modified by, adult experiences of intimate partner violence (IPV).

methodsIn-person interviews collected information regarding history of childhood abuse and IPV from 2,928 women aged 18-49 years old prior to 16 weeks of gestation. PTSD was assessed using the PTSD Checklist-Civilian Version. Multivariate logistic regressions were used to estimate odds ratios (ORs) and 95% confidence intervals (CIs).

resultsCompared to women with no childhood abuse, the odds of PTSD were increased 4.31-fold for those who reported physical abuse only (95% CI, 2.18-8.49), 5.33-fold for sexual abuse only (95% CI, 2.38-11.98), and 8.03-fold for those who reported physical and sexual abuse (95% CI, 4.10-15.74). Mediation analysis showed 13% of the childhood abuse-PTSD association was mediated by IPV. Furthermore, high odds of PTSD were noted among women with histories of childhood abuse and IPV compared with women who were not exposed to either (OR = 20.20; 95% CI, 8.18-49.85).

conclusionsChildhood abuse is associated with increased odds of PTSD during early pregnancy. The odds of PTSD were particularly elevated among women with a history of childhood abuse and IPV. Efforts should be made to prevent childhood abuse and mitigate its effects on women's mental health.

Indexed as

AdolescentAdultAdult Survivors of Child AbuseFemaleHumansIntimate Partner ViolenceMiddle AgedPeruPopulation SurveillancePregnancyPregnant PeoplePrevalenceRisk FactorsSex OffensesSocioeconomic FactorsStress Disorders, Post-TraumaticChildhood abuseEarly pregnancyPeruPTSD

Identifiers

PMID29079333
PMCPMC5820025
OpenAlexW2763866358

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.