ReviewInfectious disease clinics of North America2017
Influence of Aging and Environment on Presentation of Infection in Older Adults.
Review in Infectious disease clinics of North America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 2 of them syntheses that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
58 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Machine learning-based infection diagnostic and prognostic models in post-acute care settings: a systematic review.Journal of the American Medical Informatics Association : JAMIA · 2025Pooled it
- Impact of influenza, herpes zoster, and pneumococcal vaccinations on the incidence of cardiovascular events in subjects aged over 65 years: a systematic review.GeroScience · 2023Pooled it
- Developing and validating a sequence-aware deep learning model for infection risk prediction in home care.International journal of medical informatics · 2026Article
- Trends in Enterobacteriaceae Resistance Patterns: A Nine-Year Retrospective Study From North Lebanon.Health science reports · 2026Article
- Applying a gender and equity matrix for a contextualized antimicrobial stewardship intervention in Pakistan.Health policy and planning · 2026Article
- Exploring how older adults perceived the impact of infectious diseases and vaccines on ageing: a cross-sectional study in France.BMC geriatrics · 2026Article
- Article
- Application of artificial intelligence in geriatric infection: recent advances and prospects.Frontiers in cellular and infection microbiology · 2026Review
- Global research trends of immunosenescence and immunotherapy: A bibliometric study.Human vaccines & immunotherapeutics · 2025Review
- Preoperative performance status was associated with postoperative fatal complications in elderly patients with refractory ulcerative colitis.World journal of gastrointestinal surgery · 2025Article
- Metabolic regulation of immunological aging.Nature aging · 2025Review
- [Atypical clinical and mortality in older adults hospitalized with COVID-19 pneumonia].Revista medica del Instituto Mexicano del Seguro Social · 2025Observational
- Swabs versus native specimens in severe head and neck infections: a prospective pilot study and suggestions for clinical management.Oral and maxillofacial surgery · 2025Article
- A critical role of NNature immunology · 2025Article
- An Analysis of Bacterial Infection Distribution in the Elderly, and Their Clinical and Laboratory Profiles: Aging and Bacterial Infection.Infectious diseases & clinical microbiology · 2025Article
- Review
- Drug-associated infections and infestations in older adults with tumor necrosis factor-alpha inhibitors: a real-world retrospective and pharmacovigilance study.Frontiers in pharmacology · 2025Article
- Trends and characteristics of hospitalisation and mortality among centenarians in old-age homes and communities: a territory-wide study in Hong Kong, 2012-2021.BMJ public health · 2025Article
- The desire of autonomy: A lever for vaccination of the elderly? Results of a qualitative study.Human vaccines & immunotherapeutics · 2024Article
- Thermal Comfort Conditions and Mortality in Brazil.International journal of environmental research and public health · 2024Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
In older adults, pathophysiologic, clinical, and environmental factors all affect the presentation of infections. We explore how age-related changes influence the manifestation and evaluation of infections in this population. Specific topics include immunosenescence, age-related organ-specific physiologic changes, and frailty. We also describe clinical factors influencing infection risk and presentation in older adults, including temperature regulation, cognitive decline, and malnutrition. Finally, we discuss the influence of the setting in which older adults reside on the clinical evaluation of infection. Understanding the influence of all these changes may facilitate the prevention, early recognition, and treatment of infections in older adults.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.