Evidence map›Paper›PMID 29079076›Full record

ReviewJournal of molecular and cellular cardiology2018

Reproducibility of science: Fraud, impact factors and carelessness.

D A Eisner

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of molecular and cellular cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 79 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Positive aspects of negative data.Journal of molecular and cellular cardiology plus · 2022
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. What has changed after the COVID-19 pandemic in the publication process? A look-back to "Transfusion clinique et biologique".Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine · 2021
    Article
  15. Pseudoreplication in physiology: More means less.The Journal of general physiology · 2021
    Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Genetic Ancestry Analysis Reveals Misclassification of Commonly Used Cancer Cell Lines.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

D A EisnerUnit of Cardiac Physiology, Division of Cardiovascular Sciences, Manchester Academic Health Sciences Centre, 3.18 Core Technology Facility, University of Manchester, 46 Grafton ST, Manchester M13 9NT, UK. Electronic address: eisner@manchester.ac.uk.
Manchester Academic Health Science Centre · GB

Funding

British Heart Foundation CH/2000004/12801
6 · The paper itself

Abstract

There is great concern that results published in a large fraction of biomedical papers may not be reproducible. This article reviews the evidence for this and considers some of the factors that are responsible and how the problem may be solved. One issue is scientific fraud. This, in turn, may result from pressures put on scientists to succeed including the need to publish in "high impact" journals. I emphasise the importance of judging the quality of the science itself as opposed to using surrogate metrics. The other factors discussed include problems of experimental design and statistical analysis of the work. It is important that these issues are addressed by the scientific community before others impose draconian regulations.

Indexed as

Journal Impact FactorScientific MisconductPeriodicals as TopicPublication BiasReproducibility of ResultsFraudReproducibility

Identifiers

PMID29079076
PMCPMC6565841
OpenAlexW2765493561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.