Evidence map›Paper›PMID 29078783›Full record

ArticleVirology journal2017

A novel polyomavirus from the nasal cavity of a giant panda (Ailuropoda melanoleuca).

Dunwu Qi, Tongling Shan, Zhijian Liu, Xutao Deng, Zhihe Zhang, Wenlei Bi, Jacob Robert Owens, Feifei Feng, Lisong Zheng, Feng Huang and 3 more

Open access · goldAbstract read
In one paragraph

Article in Virology journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Dunwu QiSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu Research Base of Giant Panda Breeding, Chengdu, Sichuan, 610081, China.
Tongling ShanShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, China.
Zhijian LiuDepartment of Microbiology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, 212013, China.
Xutao DengBlood Systems Research Institute, San Francisco, California, 94118, USA.
Zhihe ZhangSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu Research Base of Giant Panda Breeding, Chengdu, Sichuan, 610081, China.
Wenlei BiSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu Research Base of Giant Panda Breeding, Chengdu, Sichuan, 610081, China.
Jacob Robert OwensSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu Research Base of Giant Panda Breeding, Chengdu, Sichuan, 610081, China.
Feifei FengSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu Research Base of Giant Panda Breeding, Chengdu, Sichuan, 610081, China.
Lisong ZhengLiziping Nature Reserve, YaAn, Sichuan Province, Sichuan, 625499, China.
Feng HuangLiziping Nature Reserve, YaAn, Sichuan Province, Sichuan, 625499, China.
Eric DelwartBlood Systems Research Institute, San Francisco, California, 94118, USA.
Rong HouSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu Research Base of Giant Panda Breeding, Chengdu, Sichuan, 610081, China. hourong2000@panda.org.cn.
Wen ZhangDepartment of Microbiology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, 212013, China. z0216wen@yahoo.com.
Chengdu Research Base of Giant Panda Breeding · CNBlood Systems Research Institute · USFanjingshan National Nature Reserve · CNJiangsu University · CNShanghai Veterinary Research Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPolyomaviruses infect a wide variety of mammalian and avian hosts with a broad spectrum of outcomes including asymptomatic infection, acute systemic disease, and tumor induction.

methodsViral metagenomics and general PCR methods were used to detected viral nucleic acid in the samples from a diseased and healthy giant pandas.

resultsA novel polyomavirus, the giant panda polyomavirus 1 (GPPyV1) from the nasal cavity of a dead giant panda (Ailuropoda melanoleuca) was characterized. The GPPyV1 genome is 5144 bp in size and reveals five putative open-reading frames coding for the classic small and large T antigens in the early region, and the VP1, VP2 and VP3 capsid proteins in the late region. Phylogenetic analyses of the large T antigen of the GPPyV1 indicated GPPyV1 belonged to a putative new species within genus Deltapolyomavirus, clustering with four human polyomavirus species. The GPPyV1 VP1 and VP2 clustered with genus Alphapolyomavirus. Our epidemiologic study indicated that this novel polyomavirus was also detected in nasal swabs and fecal samples collected from captive healthy giant pandas.

conclusionA novel polyomavirus was detected in giant pandas and its complete genome was characterized, which may cause latency infection in giant pandas.

Indexed as

AnimalsGenes, ViralGenome, ViralGenomicsNasal CavityPhylogenyPolyomavirusUrsidaeWhole Genome SequencingComplete genomeGiant pandaPolyomavirus

Identifiers

PMID29078783
PMCPMC5658932
OpenAlexW2766559115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.