Evidence map›Paper›PMID 29078401›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Development of functional ectopic compound eyes in scarabaeid beetles by knockdown of

Eduardo E Zattara, Anna L M Macagno, Hannah A Busey, Armin P Moczek

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Insect opsins and evo-devo: what have we learned in 25 years?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eduardo E ZattaraDepartment of Biology, Indiana University, Bloomington, IN 47405; ezattara@gmail.com.ORCID 0000-0002-9947-9036
Anna L M MacagnoDepartment of Biology, Indiana University, Bloomington, IN 47405.
Hannah A BuseyDepartment of Biology, Indiana University, Bloomington, IN 47405.
Armin P MoczekDepartment of Biology, Indiana University, Bloomington, IN 47405.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Complex traits like limbs, brains, or eyes form through coordinated integration of diverse cell fates across developmental space and time, yet understanding how complexity and integration emerge from uniform, undifferentiated precursor tissues remains limited. Here, we use ectopic eye formation as a paradigm to investigate the emergence and integration of novel complex structures following massive ontogenetic perturbation. We show that down-regulation via RNAi of a single head patterning gene-

Indexed as

AnimalsBody PatterningColeopteraCompound Eye, ArthropodDown-RegulationEye ProteinsGene Expression Regulation, DevelopmentalLens, CrystallineRetinaRNA InterferenceUp-RegulationEye Proteinscomplex trait evolutiondevelopmental bufferingex situ developmentorganoidRNA-seq

Identifiers

PMID29078401
PMCPMC5692598

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.