Evidence map›Paper›PMID 29078349›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Requirement of zinc transporter ZIP10 for epidermal development: Implication of the ZIP10-p63 axis in epithelial homeostasis.

Bum-Ho Bin, Jinhyuk Bhin, Mikiro Takaishi, Koh-Ei Toyoshima, Saeko Kawamata, Kana Ito, Takafumi Hara, Takashi Watanabe, Tarou Irié, Teruhisa Takagishi and 12 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 64 citations in OpenAlex.

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  15. Zinc and Zinc Transporters in Dermatology.International journal of molecular sciences · 2022
    Review
  16. Article
  17. Article
  18. Zinc in Dog Nutrition, Health and Disease: A Review.Animals : an open access journal from MDPI · 2021
    Review
  19. The role of labile ZnMolecular and cellular biochemistry · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 10 institutions in 3 countries.

Bum-Ho BinDivision of Pathology, Department of Oral Diagnostic Sciences, School of Dentistry, Showa University, Tokyo 142-8555, Japan; bbh82429@gmail.com fukada@ph.bunri-u.ac.jp.
Jinhyuk BhinDivision of Molecular Carcinogenesis, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
Mikiro TakaishiDepartment of Dermatology, Kochi Medical School, Kochi University, Nankoku 783-8505, Japan.
Koh-Ei ToyoshimaLaboratory for Organ Regeneration, RIKEN Center for Developmental Biology, Kobe 650-0047, Japan.
Saeko KawamataMolecular and Cellular Physiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima 770-8514, Japan.
Kana ItoMolecular and Cellular Physiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima 770-8514, Japan.
Takafumi HaraMolecular and Cellular Physiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima 770-8514, Japan.
Takashi WatanabeLaboratory for Integrative Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama 230-0045, Japan.
Tarou IriéDivision of Pathology, Department of Oral Diagnostic Sciences, School of Dentistry, Showa University, Tokyo 142-8555, Japan.
Teruhisa TakagishiMolecular and Cellular Physiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima 770-8514, Japan.
Su-Hyon LeeBio Solution Corporation, Seoul 139-743, Republic of Korea.
Haeng-Sun JungBio Solution Corporation, Seoul 139-743, Republic of Korea.
Sangchul RhoInstitute of Environmental and Energy Technology, Pohang University of Science and Technology, Pohang 37673, Republic of Korea.
Juyeon SeoAmorepacific R&D Unit, Beauty in Longevity Science Research Division, Beauty Food Research Team, Youngin 17074, Republic of Korea.
Dong-Hwa ChoiGyeonggi Bio Center, Gyeonggi Institute of Science and Technology Promotion, Suwon 443-270, Republic of Korea.
Daehee HwangDepartment of New Biology, Daegu Gyeongbuk Institute of Science and Technology, Daegu 42988, Republic of Korea.
Haruhiko KosekiLaboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama 230-0042, Japan.
Osamu OharaLaboratory for Integrative Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama 230-0045, Japan.
Shigetoshi SanoDepartment of Dermatology, Kochi Medical School, Kochi University, Nankoku 783-8505, Japan.
Takashi TsujiLaboratory for Organ Regeneration, RIKEN Center for Developmental Biology, Kobe 650-0047, Japan.
Kenji MishimaDivision of Pathology, Department of Oral Diagnostic Sciences, School of Dentistry, Showa University, Tokyo 142-8555, Japan.
Toshiyuki FukadaDivision of Pathology, Department of Oral Diagnostic Sciences, School of Dentistry, Showa University, Tokyo 142-8555, Japan; bbh82429@gmail.com fukada@ph.bunri-u.ac.jp.
Tokushima Bunri University · JPRIKEN Center for Integrative Medical Sciences · JPShowa University · JPKōchi University · JPKorea Bio Solution (South Korea) · KRAmorepacific (South Korea) · KRDaegu Gyeongbuk Institute of Science and Technology · KRGyeonggi College of Science and Technology · KROncode Institute · NLPohang University of Science and Technology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin tissues, in particular the epidermis, are severely affected by zinc deficiency. However, the zinc-mediated mechanisms that maintain the cells that form the epidermis have not been established. Here, we report that the zinc transporter ZIP10 is highly expressed in the outer root sheath of hair follicles and plays critical roles in epidermal development. We found that ZIP10 marked epidermal progenitor cell subsets and that ablating

Indexed as

AnimalsCations, DivalentCation Transport ProteinsCell DifferentiationCell ProliferationEmbryo, MammalianGene Expression ProfilingGene Expression Regulation, DevelopmentalHair FollicleHeLa CellsHomeostasisHumansIon TransportMiceMice, TransgenicPhosphoproteinsCations, DivalentCation Transport ProteinsLgr6 protein, mousePhosphoproteinsReceptors, G-Protein-CoupledTrans-ActivatorsTrp63 protein, mouseZincZIP10 protein, mousedevelopmenthair follicleskin epidermiszinc transporterZIP10

Identifiers

PMID29078349
PMCPMC5699059
OpenAlexW2765599697

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.