Evidence map›Paper›PMID 29078335›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Structural insights into binding of STAC proteins to voltage-gated calcium channels.

Siobhan M Wong King Yuen, Marta Campiglio, Ching-Chieh Tung, Bernhard E Flucher, Filip Van Petegem

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 67 citations in OpenAlex.

  1. Article
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  7. Inactivation of CaV1 and CaV2 channels.The Journal of general physiology · 2025
    Review
  8. Review
  9. CaNature communications · 2024
    Article
  10. Article
  11. Voltage-induced calcium release inProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. CaHandbook of experimental pharmacology · 2023
    Article
  17. Article
  18. Article
  19. Structures of the junctophilin/voltage-gated calcium channel interface reveal hot spot for cardiomyopathy mutations.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Siobhan M Wong King YuenDepartment of Biochemistry and Molecular Biology, University of British Columbia, V6T 1Z3 Vancouver, BC, Canada.
Marta CampiglioDepartment of Physiology and Medical Physics, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Ching-Chieh TungDepartment of Biochemistry and Molecular Biology, University of British Columbia, V6T 1Z3 Vancouver, BC, Canada.
Bernhard E FlucherDepartment of Physiology and Medical Physics, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0002-5255-4705
Filip Van PetegemDepartment of Biochemistry and Molecular Biology, University of British Columbia, V6T 1Z3 Vancouver, BC, Canada; filip.vanpetegem@gmail.com.ORCID 0000-0003-2728-8537
University of British Columbia · CAInnsbruck Medical University · AT

Funding

Austrian Science Fund FWF P 27031Austrian Science Fund FWF T 855CIHR MOP-119608
6 · The paper itself

Abstract

Excitation-contraction (EC) coupling in skeletal muscle requires functional and mechanical coupling between L-type voltage-gated calcium channels (Ca

Indexed as

Adaptor Proteins, Signal TransducingAnimalsBinding SitesCalciumCalcium Channels, L-TypeCalcium SignalingCleft PalateCrystallography, X-RayExcitation Contraction CouplingHumansMalignant HyperthermiaMembrane ProteinsMuscle, SkeletalMutationMyotonia CongenitaProtein IsoformsAdaptor Proteins, Signal TransducingCalciumCalcium Channels, L-TypeMembrane ProteinsProtein IsoformsRyanodine Receptor Calcium Release Channeldisease mutationmuscle excitation–contraction couplingSTAC adaptor proteinsvoltage-gated calcium channelX-ray crystallography

Identifiers

PMID29078335
PMCPMC5692558
OpenAlexW2766939625

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.