ArticleProceedings of the National Academy of Sciences of the United States of America2017
Early rearing history influences oxytocin receptor epigenetic regulation in rhesus macaques.
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Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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31citing papers in PubMed
13.9field-weighted citation impact, top 1% of its field
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Who cites it
31 citing papers in PubMed, 71 citations in OpenAlex.
- Early life adversity, oxytocin system alterations, and addiction vulnerability: a narrative review.Psychopharmacology · 2026Review
- Genetic Architecture of Immune Cell DNA Methylation in the Rhesus Macaque.Molecular ecology · 2025Article
- Early parental deprivation during primate infancy has a lifelong impact on gene expression in the male marmoset brain.Scientific reports · 2024Article
- New policies on skin-to-skin contact warrant an oxytocin-based perspective on perinatal health care.Frontiers in psychology · 2024Article
- Review of Major Social Determinants of Health in Schizophrenia-Spectrum Psychotic Disorders: III. Biology.Schizophrenia bulletin · 2023Article
- The Role of Oxytocin in Early-Life-Stress-Related Neuropsychiatric Disorders.International journal of molecular sciences · 2023Review
- Vasopressin, and not oxytocin, receptor gene methylation is associated with individual differences in receptive joint attention in chimpanzees (Pan troglodytes).Autism research : official journal of the International Society for Autism Research · 2023Article
- Genetic and epigenetic effects on couple adjustment in context of romantic relationship: A scoping systematic review.Frontiers in genetics · 2023Article
- Involvement of oxytocin receptor deficiency in psychiatric disorders and behavioral abnormalities.Frontiers in cellular neuroscience · 2023Review
- Oxytocin-based therapies for treatment of Prader-Willi and Schaaf-Yang syndromes: evidence, disappointments, and future research strategies.Translational psychiatry · 2022Review
- Oxytocin and Vasopressin Levels and Related Factors in Adolescents with Social Phobia and Other Anxiety Disorders.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2022Article
- The oxytocin system and early-life experience-dependent plastic changes.Journal of neuroendocrinology · 2021Review
- Effect of early life social adversity on drug abuse vulnerability: Focus on corticotropin-releasing factor and oxytocin.Neuropharmacology · 2021Review
- Oxytocin promotes prosocial behavior and related neural responses in infant macaques at-risk for compromised social development.Developmental cognitive neuroscience · 2021Article
- Social Isolation and Enrichment Induce Unique miRNA Signatures in the Prefrontal Cortex and Behavioral Changes in Mice.iScience · 2020Article
- Methylation of OXT and OXTR genes, central oxytocin, and social behavior in female macaques.Hormones and behavior · 2020Article
- Is Oxytocin "Nature's Medicine"?Pharmacological reviews · 2020Review
- Pathways linking childhood trauma to rural, unmarried, African American father involvement through oxytocin receptor gene methylation.Developmental psychology · 2020Article
- What is resilience: an affiliative neuroscience approach.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2020Article
- Epigenomics and gene regulation in mammalian social systems.Current zoology · 2020Article
Corrections and comments
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Authors and funding
20 authors at 7 institutions in 4 countries.
Maggie BakerSection of Comparative Behavioral Genomics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, MD 20852.
Stephen G LindellSection of Comparative Behavioral Genomics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, MD 20852.
Carlos A DriscollSection of Comparative Behavioral Genomics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, MD 20852.
Zhifeng ZhouLaboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD 20892.
Qiaoping YuanLaboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD 20892.
Melanie L SchwandtLaboratory of Clinical Studies, National Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD 20892.
Isaac Miller-CrewsSection of Comparative Behavioral Genomics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, MD 20852.
Elizabeth A SimpsonSection of Comparative Ethology, Eunice Shriver Kennedy National Institute of Child Health and Human Development, NIH, Poolesville, MD 20837.
Annika PauknerSection of Comparative Ethology, Eunice Shriver Kennedy National Institute of Child Health and Human Development, NIH, Poolesville, MD 20837.
Pier Francesco FerrariInstitute des Sciences Cognitives Mar Jeannerod, CNRS, Université Claude Bernard Lyon, 69675 Bron Cedex, France.
Ravi Kumar SindhuSection of Comparative Behavioral Genomics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, MD 20852.
Muslima RazaqyarSection of Comparative Behavioral Genomics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, MD 20852.
Wolfgang H SommerDepartment of Psychopharmacology, Central Institute of Mental Health, Heidelberg University, 68159 Mannheim, Germany.
Juan F LopezDepartment of Psychiatry, University of Michigan Medical School, Ann Arbor, MI 48109.
Robert C ThompsonDepartment of Psychiatry, University of Michigan Medical School, Ann Arbor, MI 48109.
David GoldmanLaboratory of Clinical Studies, National Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD 20892.
Markus HeiligCenter for Social and Affective Neuroscience, Department of Clinical and Experimental Medicine, Linköping University, S-58183 Linköping, Sweden.
J Dee HigleyDepartment of Psychology, Brigham Young University, Provo, UT 84602.
Stephen J SuomiSection of Comparative Ethology, Eunice Shriver Kennedy National Institute of Child Health and Human Development, NIH, Poolesville, MD 20837.
Christina S BarrSection of Comparative Behavioral Genomics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, MD 20852; cbarr@mail.nih.gov.
National Institute on Alcohol Abuse and Alcoholism · USEunice Kennedy Shriver National Institute of Child Health and Human Development · USUniversity of Michigan–Ann Arbor · USBrigham Young University · USCentre National de la Recherche Scientifique · FRHeidelberg University · DELinköping University · SE
Funding
Integrative genetics of behavior with high throughput technologiesZIAAA000301 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI GOLDMAN, DAVID · 2009 to 2025
$68.6MCross-Species Genetic and Epigenetic Studies of Stress Response and RewardZIAAA000311 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI BARR, CHRISTINA · 2010 to 2020
$14.0MProject IV: Investigating the Mirror Neuron System in austism spectrum disorderP01HD064653 · NICHD · UNIV OF MARYLAND, COLLEGE PARK · PI FOX, NATHAN A · 2010 to 2020
$11.9MNICHD NIH HHS P01 HD064653
Abstract
Adaptations to stress can occur through epigenetic processes and may be a conduit for informing offspring of environmental challenge. We employed ChIP-sequencing for H3K4me3 to examine effects of early maternal deprivation (peer-rearing, PR) in archived rhesus macaque hippocampal samples (male,
Indexed as
Adaptation, PsychologicalAllelesAnimalsAnxiety, SeparationEpigenesis, GeneticFemaleHippocampusHistonesMacaca mulattaMaleMaternal DeprivationOxytocinPolymorphism, Single NucleotideReceptors, OxytocinStress, PhysiologicalHistonesOxytocinReceptors, Oxytocinepigeneticmaternal careoxytocinprimatestress
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.