Evidence map›Paper›PMID 29078083›Full record

Trial reportCortex; a journal devoted to the study of the nervous system and behavior2017

The asymmetrical effect of leftward and rightward prisms on intact visuospatial cognition.

Selene Schintu, Ivan Patané, Michela Caldano, Romeo Salemme, Karen T Reilly, Laure Pisella, Alessandro Farnè

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Cortex; a journal devoted to the study of the nervous system and behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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  7. Review
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  14. Left-shifting prism adaptation boosts reward-based learning.Cortex; a journal devoted to the study of the nervous system and behavior · 2018
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Selene SchintuIntegrative Multisensory Perception Action & Cognition Team (ImpAct), Lyon Neuroscience Research Center, INSERM U1028, CNRS UMR5292, Lyon, France; University Lyon 1, Lyon, France; Hospices Civils de Lyon, Neuro-immersion & Mouvement et Handicap, Lyon, France. Electronic address: selene.schintu@inserm.fr.
Ivan PatanéIntegrative Multisensory Perception Action & Cognition Team (ImpAct), Lyon Neuroscience Research Center, INSERM U1028, CNRS UMR5292, Lyon, France; University Lyon 1, Lyon, France; Hospices Civils de Lyon, Neuro-immersion & Mouvement et Handicap, Lyon, France; Department of Psychology, University of Bologna, Bologna, Italy.
Michela CaldanoDepartment of Psychology, University of Torino, Torino, Italy.
Romeo SalemmeIntegrative Multisensory Perception Action & Cognition Team (ImpAct), Lyon Neuroscience Research Center, INSERM U1028, CNRS UMR5292, Lyon, France; University Lyon 1, Lyon, France; Hospices Civils de Lyon, Neuro-immersion & Mouvement et Handicap, Lyon, France.
Karen T ReillyIntegrative Multisensory Perception Action & Cognition Team (ImpAct), Lyon Neuroscience Research Center, INSERM U1028, CNRS UMR5292, Lyon, France; University Lyon 1, Lyon, France; Hospices Civils de Lyon, Neuro-immersion & Mouvement et Handicap, Lyon, France.
Laure PisellaIntegrative Multisensory Perception Action & Cognition Team (ImpAct), Lyon Neuroscience Research Center, INSERM U1028, CNRS UMR5292, Lyon, France; University Lyon 1, Lyon, France; Hospices Civils de Lyon, Neuro-immersion & Mouvement et Handicap, Lyon, France.
Alessandro FarnèIntegrative Multisensory Perception Action & Cognition Team (ImpAct), Lyon Neuroscience Research Center, INSERM U1028, CNRS UMR5292, Lyon, France; University Lyon 1, Lyon, France; Hospices Civils de Lyon, Neuro-immersion & Mouvement et Handicap, Lyon, France.

Funding

Intramural NIH HHS Z99 NS999999
6 · The paper itself

Abstract

Rightward prismatic adaptation (RPA) can reduce neglect symptoms in patients whereas adaptation to leftward deviating prisms (LPA) can induce neglect-like behavior in healthy subjects. One influential anatomo-functional model of prismatic adaptation (PA) postulates that it inhibits activity of the posterior parietal cortex (PPC) contralateral to the prismatic deviation. By hypo-activating the PPC and thus eventually acting on interhemispheric balance, both LPA and RPA could possibly affect visuospatial perception in healthy subjects, however, such behavioral modulation has seldom been reported after RPA. In the light of recent evidence showing that LPA-induced visuospatial shift need time to develop we hypothesized that RPA might induce significant changes in visuospatial cognition on a longer time scale. We thus assessed the Landmark task, as well as sensorimotor aftereffects, several times over 8 h after a single session of either LPA or RPA. In agreement with previous reports, sensorimotor effects were symmetrical and long-lasting, with both LPA and RPA inducing shifts of comparable amplitudes in the direction opposite to the deviation that lasted up to 8 h. Visuospatial cognition assessed by Landmark performance, was also significantly modulated for up to 8 h, but only after LPA. Interestingly, the timing and direction of this modulation differed according to participants' baseline bias. An initial leftward bias led to a rapid, but short-lasting rightward shift, whereas an initial rightward bias led to a slower-developing and longer-lasting leftward shift. These findings shed new light on a so-far relatively overlooked feature of spatial cognition that may interact with the effect of PA: the state of the visuospatial system prior to PA should be taken into account when attempting to understand and modulate visuospatial cognition in healthy and brain-damaged populations. This highlights the need for refining current models of PA's mechanisms of action.

Indexed as

Adaptation, PhysiologicalAdultCognitionFemaleFunctional LateralityHumansMaleParietal LobePhotic StimulationSpace PerceptionVisual FieldsVisual PerceptionYoung AdultLine bisectionPlasticityPrism adaptationPseudoneglectVisuospatial cognition

Identifiers

PMID29078083
PMCPMC5716840

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.