Evidence map›Paper›PMID 29077960›Full record

Trial reportPhysical therapy2017

Locomotor Training and Strength and Balance Exercises for Walking Recovery After Stroke: Response to Number of Training Sessions.

Dorian K Rose, Stephen E Nadeau, Samuel S Wu, Julie K Tilson, Bruce H Dobkin, Qinglin Pei, Pamela W Duncan

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Physical therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06234124 (Characterization and Clinical Trial of a Variable Friction Shoe, a New Paradigm of Reduced-constraint Locomotor Therapy for People Exhibiting Foot Drop Due to Stroke), which is not on this map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06234124 narecruitingnot on this mapstarted 2024, after this paper: background citation

Characterization and Clinical Trial of a Variable Friction Shoe, a New Paradigm of Reduced-constraint Locomotor Therapy for People Exhibiting Foot Drop Due to Stroke

TypeinterventionalSponsorShirley Ryan AbilityLabRan2024 to 2027Enrolled50ConditionsStrokeArmsVariable Friction Shoe Training, Ankle Foot Orthosis (AFO) Training
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Effect of mobile application types on stroke rehabilitation: a systematic review.Journal of neuroengineering and rehabilitation · 2023
    Pooled it
  2. Physical fitness training for stroke patients.The Cochrane database of systematic reviews · 2020
    Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Review
  8. Article
  9. Optimal Reactive Balance Training Characteristics Poststroke: Secondary Analysis of a Clinical Trial.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026
    Article
  10. Home-Based Gait Interventions for Adults with Stroke: A Scoping Review.Archives of rehabilitation research and clinical translation · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
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  17. Article
  18. Review
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  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Dorian K RoseDepartment of Physical Therapy, University of Florida, PO Box 100154, Gainesville, FL 32610-0154 (USA), and Malcom Randall VAMC Research Service and Brain Rehabilitation Research Center, Gainesville, Florida.
Stephen E NadeauMalcom Randall VAMC Research Service, Brain Rehabilitation Research Center, and Department of Neurology, University of Florida.
Samuel S WuDepartment of Biostatistics, University of Florida.
Julie K TilsonDivision of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, California.
Bruce H DobkinDepartment of Neurology, University of California, California.
Qinglin PeiDepartment of Biostatistics, University of Florida.
Pamela W DuncanDepartment of Neurology and Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina.

Funding

Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI Stephen D Anton · 2007 to 2026
$22.8M
Locomotor Experience Applied Post-Stroke (LEAPS)R01NS050506 · NINDS · UNIVERSITY OF FLORIDA · PI DUNCAN, PAMELA W. · 2005 to 2009
$13.3M
NCATS NIH HHS UL1 TR001427NIA NIH HHS P30 AG028740NINDS NIH HHS R01 NS050506
6 · The paper itself

Abstract

backgroundEvidence-based guidelines are needed to inform rehabilitation practice, including the effect of number of exercise training sessions on recovery of walking ability after stroke.

objectiveThe objective of this study was to determine the response to increasing number of training sessions of 2 interventions-locomotor training and strength and balance exercises-on poststroke walking recovery.

designThis is a secondary analysis of the Locomotor Experience Applied Post-Stroke (LEAPS) randomized controlled trial.

settingSix rehabilitation sites in California and Florida and participants' homes were used.

participantsParticipants were adults who dwelled in the community (N=347), had had a stroke, were able to walk at least 3 m (10 ft) with assistance, and had completed the required number of intervention sessions.

interventionParticipants received 36 sessions (3 times per week for 12 weeks), 90 minutes in duration, of locomotor training (gait training on a treadmill with body-weight support and overground training) or strength and balance training. MEASUREMENTS: Talking speed, as measured by the 10-Meter Walk Test, and 6-minute walking distance were assessed before training and following 12, 24, and 36 intervention sessions.

resultsParticipants at 2 and 6 months after stroke gained in gait speed and walking endurance after up to 36 sessions of treatment, but the rate of gain diminished steadily and, on average, was very low during the 25- to 36-session epoch, regardless of treatment type or severity of impairment. LIMITATIONS: Results may not generalize to people who are unable to initiate a step at 2 months after stroke or people with severe cardiac disease.

conclusionsIn general, people who dwelled in the community showed improvements in gait speed and walking distance with up to 36 sessions of locomotor training or strength and balance exercises at both 2 and 6 months after stroke. However, gains beyond 24 sessions tended to be very modest. The tracking of individual response trajectories is imperative in planning treatment.

Indexed as

Resistance TrainingStroke RehabilitationAgedFemaleHumansMaleMiddle AgedPostural BalanceRecovery of FunctionSingle-Blind MethodStrokeTreatment OutcomeWalkingWalking Speed

Identifiers

PMID29077960
PMCPMC6075074

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.