Evidence map›Paper›PMID 29077730›Full record

ArticlePloS one2017

Detection of central visual field defects in early glaucomatous eyes: Comparison of Humphrey and Octopus perimetry.

Gloria Roberti, Gianluca Manni, Ivano Riva, Gabor Holló, Luciano Quaranta, Luca Agnifili, Michele Figus, Sara Giammaria, Davide Rastelli, Francesco Oddone

Open access · goldAbstract readComparative Study
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 3 countries.

Gloria RobertiIRCSS-Fondazione GB Bietti, Rome, Italy.ORCID http://orcid.org/0000-0001-8788-5785
Gianluca ManniIRCSS-Fondazione GB Bietti, Rome, Italy.
Ivano RivaIRCSS-Fondazione GB Bietti, Rome, Italy.
Gabor HollóDepartment of Ophthalmology, Semmelweis University, Budapest, Hungary.
Luciano QuarantaSection of Ophthalmology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health University of Brescia, Brescia, Italy.
Luca AgnifiliOphthalmology Clinic, Department of Medicine and Aging Science, "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy.
Michele FigusDepartment of Neurosciences, University of Pisa, Pisa, Italy.
Sara GiammariaUniversity of Rome Campus Biomedico, Rome, Italy.
Davide RastelliDSCMT, University of Rome Tor Vergata, Rome, Italy.
Francesco OddoneIRCSS-Fondazione GB Bietti, Rome, Italy.
Fondazione G.B. Bietti · ITUniversity of Rome Tor Vergata · ITSemmelweis University · HUUniversità Campus Bio-Medico · ITUniversity of Brescia · ITUniversity of Chieti-Pescara · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare the detection rate of central visual field defect (CVFD) between the 30-degree Octopus G1 program (Dynamic strategy) and the HFA 10-2 SITA-Standard test in early glaucoma eyes not showing any CVFD on the HFA 24-2 SITA-Standard test.

methodsOne eye of 41 early glaucoma patients without CVFD in the central 10° on HFA 24-2 test was tested with both the HFA 10-2 test and the Octopus G1 program 15 minutes apart, in random order. The primary outcome measure was the comparison of CVFD detection rates. Secondary outcome measures comprised the agreement in detecting CVFD, and the comparison of test durations and the numbers of depressed test points outside the central 10-degree area between the HFA 24-2 test and the Octopus G1 program.

resultsThe mean age of the population was 65.2±10.1 years, and the mean deviation with HFA 24-2 was -3.26±2.6 dB. The mean test duration was not significantly different between the tests (p = 0.13). A CVFD was present in 33 (80.4%) HFA 10-2 test and in 23 (56.0%) Octopus G1 tests (p = 0.002). The overall agreement between the HFA 10-2 and Octopus G1 examinations in classifying eyes as having or not having CVFD was moderate (Cohen's kappa 0.47). The Octopus G1 program showed 69.6% sensitivity and 100% specificity to detect CVFD in eyes where the HFA 10-2 test revealed a CVFD. The number of depressed test points (p<5%) outside the central 10° area detected with the Octopus G1 program (19.68±10.6) was significantly higher than that detected with the HFA 24-2 program (11.95±5.5, p<0.001).

conclusionBoth HFA 10-2 and Octopus G1programs showed CVFD not present at HFA 24-2 test although the agreement was moderate. The use of a single Octopus G1 examination may represent a practical compromise for the assessment of both central and peripheral visual field up to 30° eccentricity without any additional testing and increasing the total investigation time.

Indexed as

Visual FieldsAgedFemaleGlaucomaHumansMaleMiddle AgedVisual Field Tests

Identifiers

PMID29077730
PMCPMC5659771
OpenAlexW2766812433

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.