ArticleThe Journal of nervous and mental disease2017
Exploring the Relationship Between Body Mass Index and Positive Symptom Severity in Persons at Clinical High Risk for Psychosis.
Article in The Journal of nervous and mental disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 12 citations in OpenAlex.
- Sex as a moderator of the relationship between food addiction and body mass index in young non-help-seeking adults at risk for psychosis and controls.Eating and weight disorders : EWD · 2026Article
- Differences in height, weight, and BMI in patients with mood disorders, schizophrenia, and other mental disorders vs. normal controls.Frontiers in psychiatry · 2025Article
- Physical Health and Transition to Psychosis in People at Clinical High Risk.Biomedicines · 2024Article
- Association of Alexithymia With Positive Symptoms in Chinese Chronic Schizophrenia Patients With and Without Obesity.Psychiatry investigation · 2023Article
- Body composition in Japanese patients with psychiatric disorders: A cross-sectional study.Neuropsychopharmacology reports · 2021Article
- Dissecting clinical heterogeneity of bipolar disorder using multiple polygenic risk scores.Translational psychiatry · 2020Article
- Neutrophil Count Is Associated With Reduced Gray Matter and Enlarged Ventricles in First-Episode Psychosis.Schizophrenia bulletin · 2019Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Metabolic health and positive symptom severity has been investigated in schizophrenia, but not in clinical high risk (CHR) patients. We hypothesized that greater body mass index (BMI) in CHR patients would be related to less positive symptoms. We examined this relationship in CHR patients being treated with 1) no psychotropic medications (n = 58), 2) an antipsychotic (n = 14), or 3) an antidepressant without an antipsychotic (n = 10). We found no relationship between BMI and positive symptoms in unmedicated CHR patients, the majority of whom had a narrow BMI range between 20 and 30. However, in the smaller sample of CHR patients taking an antidepressant or antipsychotic, BMI was negatively correlated with positive symptoms. Although potentially underpowered, these preliminary findings provide initial steps in elucidating the relationships between metabolic health, neurochemistry, and symptom severity in CHR patients.
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