Evidence map›Paper›PMID 29077523›Full record

ReviewNucleus (Austin, Tex.)2017

Heterochromatin and DNA damage repair: Use different histone variants and relax.

Zdravko J Lorković, Frédéric Berger

Open access · goldAbstract readReview
In one paragraph

Review in Nucleus (Austin, Tex.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Epigenetics in the modern era of crop improvements.Science China. Life sciences · 2025
    Review
  4. Review
  5. Review
  6. Histone H2A variants: Diversifying chromatin to ensure genome integrity.Seminars in cell & developmental biology · 2023
    Review
  7. Article
  8. Article
  9. Review
  10. Connections between the Cell Cycle and the DNA Damage Response in Plants.International journal of molecular sciences · 2021
    Review
  11. H2A Variants inPlant communications · 2020
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Zdravko J Lorkovića Gregor Mendel Institute (GMI), Austrian Academy of Sciences, Vienna BioCenter (VBC) , Dr. Bohr-Gasse 3, Vienna , Austria.ORCID 0000-0002-3074-7258
Frédéric Bergera Gregor Mendel Institute (GMI), Austrian Academy of Sciences, Vienna BioCenter (VBC) , Dr. Bohr-Gasse 3, Vienna , Austria.
Gregor Mendel Institute of Molecular Plant Biology · AT

Funding

Austrian Science Fund FWF P 26887
6 · The paper itself

Abstract

Repair of damaged DNA requires the activation of kinases, which in turn phosphorylate diverse proteins including histone H2A.X, an event conserved from yeast to human. By combining genetics, biochemical, and cytological approaches, we recently reported that, in addition to H2A.X, phosphorylation of histone variant H2A.W.7 is required for DNA damage response in Arabidopsis. This work provides direct evidence for the functional diversification of plant-specific H2A.W histone variants, which are tightly associated with heterochromatin. We place our findings in perspective of other recent reports and discuss how DNA damage is being recognized and repaired in heterochromatin.

Indexed as

DNA DamageDNA RepairAnimalsHeterochromatinHistonesHumansModels, BiologicalHeterochromatinHistonesDNA damage responseH2A.Wheterochromatinhistone variantphosphorylation

Identifiers

PMID29077523
PMCPMC5788557
OpenAlexW2765407937

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.