Evidence map›Paper›PMID 29076991›Full record

ArticleToxins2017

Single Chain Antibody Fragment against Venom from the Snake Daboia russelii formosensis.

Chi-Hsin Lee, Yu-Ching Lee, Yueh-Lun Lee, Sy-Jye Leu, Liang-Tzung Lin, Chi-Ching Chen, Jen-Ron Chiang, Pharaoh Fellow Mwale, Bor-Yu Tsai, Ching-Sheng Hung and 1 more

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

  1. Phage display-derived alpaca nanobodies as potential therapeutics forApplied and environmental microbiology · 2024
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  2. Article
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  4. Article
  5. Review
  6. Chicken antibodies against venom proteins ofThe journal of venomous animals and toxins including tropical diseases · 2020
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Chi-Hsin LeeGraduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan. chihsine@msn.com.
Yu-Ching LeeThe Center of Translational Medicine, Taipei Medical University, Taipei 11031, Taiwan. ycl@tmu.edu.tw.
Yueh-Lun LeeGraduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan. yllee@tmu.edu.tw.
Sy-Jye LeuGraduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan. cmbsycl@tmu.edu.tw.
Liang-Tzung LinGraduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan. ltlin@tmu.edu.tw.
Chi-Ching ChenDepartment of Pathology and Laboratory Medicine, Landseed Hospital, Taoyuan 32449, Taiwan. chen3971@landseed.com.tw.
Jen-Ron ChiangCenter for Research, Diagnostics and Vaccine Development, Centers for Disease Control, Ministry of Health and Welfare, Taipei 11558, Taiwan. jrc@cdc.gov.tw.ORCID 0000-0002-7111-7279
Pharaoh Fellow MwaleSchool of Medical Laboratory Science and Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan. pmwale@medcol.mw.
Bor-Yu TsaiNavi Bio-Therapeutics Inc., Taipei 10351, Taiwan. boryutsai@navibio.com.tw.
Ching-Sheng HungDepartment of Laboratory Medicine, Wan Fang Hospital, Taipei Medical University, Taipei 11696, Taiwan. oryx@w.tmu.edu.tw.
Yi-Yuan YangSchool of Medical Laboratory Science and Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan. yangyuan@tmu.edu.tw.
Taipei Medical University · TWLandseed Hospital · TWMinistry of Health and Welfare · TWWan Fang Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Russell's vipers containing hemotoxic and neurotoxic venom commonly cause snake envenomation. Horse-derived antivenom is a specific antidote, but its production is expensive and has side effects. Developing a cost-effective and more tolerable therapeutic strategy is favorable. In this study, using glutaraldehyde-attenuated

Indexed as

AnimalsAntibodies, NeutralizingAntiveninsChickensDaboiaImmunoglobulinsReptilian ProteinsSingle-Chain AntibodiesViper VenomsAntibodies, NeutralizingAntiveninsIgYImmunoglobulinsReptilian ProteinsSingle-Chain AntibodiesViper VenomsDaboia russelii formosensis (DRF)IgY antibodyphage display technologysingle-chain variable fragment (scFv) antibody

Identifiers

PMID29076991
PMCPMC5705962
OpenAlexW2767101293

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.