ArticleThe Journal of general virology2018
Culex quinquefasciatus mosquitoes do not support replication of Zika virus.
Article in The Journal of general virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Secondary vectors of Zika Virus, a systematic review of laboratory vector competence studies.PLoS neglected tropical diseases · 2023Pooled it
- Oropouche Virus (OROV) Vaccine Development for Vulnerable Populations: Epidemiological Context, Challenges and Future Directions.Vaccines · 2026Review
- Article
- [Identification ofJugan geon-gang gwa jilbyeong · 2025Article
- Dissecting Zika virus transmission byFrontiers in microbiology · 2025Article
- The Susceptibility of Chickens to Zika Virus: A Comprehensive Study on Age-Dependent Infection Dynamics and Host Responses.Viruses · 2024Article
- Ilheus Virus (ILHV) Resistance inLife (Basel, Switzerland) · 2024Article
- Article
- Article
- Zika vector competence data reveals risks of outbreaks: the contribution of the European ZIKAlliance project.Nature communications · 2022Article
- Molecular survey of Zika virus in the animal-human interface in traditional farming.Frontiers in veterinary science · 2022Article
- Follow-Up Household Serosurvey in Northeast Brazil for Zika Virus: Sexual Contacts of Index Patients Have the Highest Risk for Seropositivity.The Journal of infectious diseases · 2021Article
- Article
- Review
- Contrasted transmission efficiency of Zika virus strains by mosquito species Aedes aegypti, Aedes albopictus and Culex quinquefasciatus from Reunion Island.Parasites & vectors · 2020Article
- Vector Competence ofPathogens (Basel, Switzerland) · 2020Article
- Forced Zika Virus Infection ofViruses · 2020Article
- Exploring Evolutionary Constraints in the Proteomes of Zika, Dengue, and Other Flaviviruses to Find Fitness-Critical Sites.Journal of molecular evolution · 2020Article
- Article
- Vector competence ofRevista panamericana de salud publica = Pan American journal of public health · 2020Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
The rapid spread of Zika virus (ZIKV) in the Americas raised many questions about the role of Culex quinquefasciatus mosquitoes in transmission, in addition to the key role played by the vector Aedes aegypti. Here we analysed the competence of Cx. quinquefasciatus (with or without Wolbachia endosymbionts) for a ZIKV isolate. We also examined the induction of RNA interference pathways after viral challenge and the production of small virus-derived RNAs. We did not observe any infection nor such small virus-derived RNAs, regardless of the presence or absence of Wolbachia. Thus, Cx. quinquefasciatus does not support ZIKV replication and Wolbachia is not involved in producing this phenotype. In short, these mosquitoes are very unlikely to play a role in transmission of ZIKV.
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