ArticleThe British journal of radiology2018
Contrast enhancement in abdominal computed tomography: influence of photon energy of different scanners.
Article in The British journal of radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 6 citations in OpenAlex.
- Optimization of high-concentration (400 mgI/mL) contrast media volume for abdominal computed tomography: a comparison between fixed-dose and total body weight-based protocols.Quantitative imaging in medicine and surgery · 2026Article
- Evaluation of the Practice of Performing Abdominal CT Scan with Manually Administered Fixed Dose of Contrast in Achieving Adequate Hepatic Enhancement: An Institutional-Based Cross-Sectional Study.Radiology research and practice · 2023Article
- Influence of beam hardening in dual-energy CT imaging: phantom study for iodine mapping, virtual monoenergetic imaging, and virtual non-contrast imaging.European radiology experimental · 2021Article
- Feasibility of Bone Mineral Density and Bone Microarchitecture Assessment Using Deep Learning With a Convolutional Neural Network.Journal of computer assisted tomographyArticle
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Authors and funding
15 authors at 2 institutions in 1 country.
Funding
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Abstract
objectiveDifferent CT scanners have different X-ray spectra and photon energies indicating that contrast enhancement vary among scanners. However, this issue has not been fully validated; therefore, we performed phantom and clinical studies to assess this difference.
methodsTwo scanners were used: scanner-A and scanner-B. In the phantom study, we compared the contrast enhancement between the scanners at tube voltage peaks of 80, 100 and 120 kVp. Then, we calculated the effective energies of the two CT scanners. In the clinical study, 40 patients underwent abdominal scanning with scanner-A and another 40 patients with scanner-B, with each group using the same scanning protocol. The contrast enhancement of abdominal organs was assessed quantitatively (based on the absolute difference between the attenuation of unenhanced scans and contrast-enhanced scans) and qualitatively. A two-tailed independent Student's t-test and or the Mann-Whitney U test were used to compare the discrepancies.
resultsIn the phantom study, contrast enhancement for scanner-B was 36.9, 32.6 and 30.8% higher than that for scanner-A at 80, 100 and 120 kVp, respectively. The effective energies were higher for scanner-A than for scanner-B. In the quantitative analysis for the clinical study, scanner-B yielded significantly better contrast enhancement of the hepatic parenchyma, pancreas, kidney, portal vein and inferior vena cava compared with that of scanner-A. The mean visual scores for contrast enhancement were also significantly higher on images obtained by scanner-B than those by scanner-A.
conclusionThere were significant differences in contrast enhancement of the abdominal organs between the compared CT scanners from two different vendors even at the same scanning and contrast parameters. Advances in knowledge: Awareness of the impact of different X-ray energies on the resultant attenuation of contrast material is important when interpreting clinical CT images.
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