ArticleACS chemical neuroscience2018
A Detailed Model of Electroenzymatic Glutamate Biosensors To Aid in Sensor Optimization and in Applications in Vivo.
Article in ACS chemical neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 30 citations in OpenAlex.
- Neuroengineering Frontiers: A Selective Review of Neural Interfaces, Brain-Machine Interactions, and Artificial Intelligence in Neurodegenerative Diseases.Applied sciences (Basel, Switzerland) · 2025Article
- Multiplexing FSCV and iGluSnFR3 Sensors Reveals Adenosine Transiently Inhibits Stimulated Dopamine and Glutamate Release.Journal of neurochemistry · 2025Article
- Enzymatic Polymer Brush Interfaces for Electrochemical Sensing in Biofluids.ACS applied bio materials · 2025Article
- Article
- Cortico-striatal action control inherent of opponent cognitive-motivational styles.bioRxiv : the preprint server for biology · 2024Article
- Improving Sensitivity and Longevity of In Vivo Glutamate Sensors with Electrodeposited NanoPt.ACS applied materials & interfaces · 2024Article
- Accelerating the development of implantable neurochemical biosensors by using existing clinically applied depth electrodes.Analytical and bioanalytical chemistry · 2023Article
- A Highly Sensitive Amperometric Glutamate Oxidase Microbiosensor Based on a Reduced Graphene Oxide/Prussian Blue Nanocube/Gold Nanoparticle Composite Film-Modified Pt Electrode.Sensors (Basel, Switzerland) · 2020Article
- Transcranial photoacoustic imaging of NMDA-evoked focal circuit dynamics in the rat hippocampus.Journal of neural engineering · 2020Article
- Article
- Frontiers in Electrochemical Sensors for Neurotransmitter Detection: Towards Measuring Neurotransmitters as Chemical Diagnostics for Brain Disorders.Analytical methods : advancing methods and applications · 2019Article
- Development of a novel micro biosensor for in vivo monitoring of glutamate release in the brain.Biosensors & bioelectronics · 2019Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Simulations conducted with a detailed model of glutamate biosensor performance describe the observed sensor performance well, illustrate the limits of sensor performance, and suggest a path toward sensor optimization. Glutamate is the most important excitatory neurotransmitter in the brain, and electroenzymatic sensors have emerged as a useful tool for the monitoring of glutamate signaling in vivo. However, the utility of these sensors currently is limited by their sensitivity and response time. A mathematical model of a typical glutamate biosensor consisting of a Pt electrode coated with a permselective polymer film and a top layer of cross-linked glutamate oxidase has been constructed in terms of differential material balances on glutamate, H
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