Evidence map›Paper›PMID 29076641›Full record

ArticleEnvironmental microbiology2017

Mi Casa es Su Casa: how an intracellular symbiont manipulates host biology.

Tamanash Bhattacharya, Irene L G Newton

Abstract read
In one paragraph

Article in Environmental microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. mBio · 2026
    Article
  2. Article
  3. Microbiology spectrum · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Symbiosis Comes of age at the 10Applied and environmental microbiology · 2019
    Review
  13. Article
  14. Review
  15. Frontiers in genetics · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Tamanash BhattacharyaDepartment of Biology, Indiana University, Bloomington, IN 47405, USA.
Irene L G NewtonDepartment of Biology, Indiana University, Bloomington, IN 47405, USA.

Funding

Determining the mechanism of Wolbachia pathogen blockingR21AI121849 · NIAID · TRUSTEES OF INDIANA UNIVERSITY · PI NEWTON, IRENE · 2017 to 2018
$420k
NIAID NIH HHS R21 AI121849
6 · The paper itself

Abstract

Wolbachia pipientis, the most common intracellular infection on the planet, infects 40% of insects as well as nematodes, isopods and arachnids. Wolbachia are obligately intracellular and challenging to study; there are no genetic tools for manipulating Wolbachia nor can they be cultured outside of host cells. Despite these roadblocks, the research community has defined a set of Wolbachia loci involved in host interaction: Wolbachia effectors. Through the use of Drosophila genetics, surrogate systems and biochemistry, the field has begun to define the toolkit Wolbachia use for host manipulation. Below we review recent findings identifying these Wolbachia effectors and point to potential, as yet uncharacterized, links between known phenotypes induced by Wolbachia infection and predicted effectors.

Identifiers

PMID29076641
PMCPMC5924462

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.