ArticleEnvironmental science & technology2017
Characterization of Individual Isopropylated and tert-Butylated Triarylphosphate (ITP and TBPP) Isomers in Several Commercial Flame Retardant Mixtures and House Dust Standard Reference Material SRM 2585.
Article in Environmental science & technology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed.
- Triphenyl phosphate promotes lipid accumulation in human mesenchymal stem cells through metabolic stress pathways.Archives of toxicology · 2026Article
- Firemaster 550 differentially alters gene expression underlying synaptic function in amygdala of prairie voles after gestational or lactational exposure.Neurotoxicology · 2026Article
- Sex-specific disruption of estrogen receptor alpha (ERα) density in the social brain neural network by Firemaster 550.Journal of the Endocrine Society · 2026Article
- Organophosphate ester flame retardants and plasticizers in house dust and Child Behavior Checklist outcomes: A nested study in the Canadian CHILD Birth Cohort.Journal of exposure science & environmental epidemiology · 2026Article
- Spatioseasonal Variability and Correlations of Particle-Bound Organophosphate Esters in Providence, Rhode Island.ACS omega · 2025Article
- An assessment of organophosphate ester mixtures and the placental transcriptome.Environment international · 2025Article
- Occupational Exposure of On-Shift Ottawa Firefighters to Flame Retardants and Polycyclic Aromatic Hydrocarbons.Toxics · 2024Article
- Children's exposure to brominated flame retardants in the home: The TESIE study.Environmental pollution (Barking, Essex : 1987) · 2024Article
- PMGeoHealth · 2024Article
- Organophosphate ester flame retardants and plasticizers in house dust and mental health outcomes among Canadian mothers: A nested prospective cohort study in CHILD.Environmental research · 2024Article
- Developmental organophosphate flame retardant exposure disrupts adult hippocampal neurogenesis in Wistar rats.Neurotoxicology · 2023Article
- Measuring semi-volatile organic compound exposures during pregnancy using silicone wristbands.Chemosphere · 2023Article
- Complex Mixtures and Multiple Stressors: Evaluating Combined Chemical Exposures and Cumulative Toxicity.Toxics · 2023Article
- Article
- Maternal organophosphate flame retardant exposure alters the developing mesencephalic dopamine system in fetal rat.Toxicological sciences : an official journal of the Society of Toxicology · 2023Article
- Hormone receptor activities of complex mixtures of known and suspect chemicals in personal silicone wristband samplers worn in office buildings.Chemosphere · 2023Article
- Skeletal effects following developmental flame-retardant exposure are specific to sex and chemical class in the adult Wistar rat.Frontiers in toxicology · 2023Article
- Impacts of Gestational FireMaster 550 Exposure on the Neonatal Cortex Are Sex Specific and Largely Attributable to the Organophosphate Esters.Neuroendocrinology · 2023Article
- Partial dust removal in vehicles does not mitigate human exposure to organophosphate esters.Environmental research · 2022Article
- Chemical contaminant exposures assessed using silicone wristbands among occupants in office buildings in the USA, UK, China, and India.Environment international · 2021Article
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4 authors.
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Abstract
Since the phase-out of pentaBDE in the early 2000s, replacement flame-retardant mixtures including Firemaster 550 (FM 550), Firemaster 600 (FM 600), and organophosphate aryl ester technical mixtures have been increasingly used to treat polyurethane foam in residential upholstered furniture. These mixtures contain isomers of isopropylated and tert-butylated triarylphosphate esters (ITPs and TBPPs), which have similar or greater neuro- and developmental toxicity compared to BDE 47 in high-throughput assays. Additionally, human exposure to ITPs and TBPPs has been demonstrated to be widespread in several recent studies; however, the relative composition of these mixtures has remained largely uncharacterized. Using available authentic standards, the present study quantified the contribution of individual ITP and TBPP isomers in four commercial flame retardant mixtures: FM 550, FM 600, an ITP mixture, and a TBPP mixture. Findings suggest similarities between FM 550 and the ITP mixture, with 2-isopropylphenyl diphenyl phosphate (2IPPDPP), 2,4-diisopropylphenyl diphenyl phosphate (24DIPPDPP), and bis(2-isopropylphenyl) phenyl phosphate (B2IPPPP) being the most prevalent ITP isomers in both mixtures. FM 600 differed from FM 550 in that it contained TBPP isomers instead of ITP isomers. These analytes were also detected and quantified in a house dust standard reference material, SRM 2585, demonstrating their environmental relevance.
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