ArticleIndian journal of pediatrics2018
Bordetella Pertussis Infection in Hospitalized Infants with Acute Bronchiolitis.
Article in Indian journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.
- Working group summary of the 2023 full update of the Finnish national guidelines for paediatric lower respiratory tract infections.Acta paediatrica (Oslo, Norway : 1992) · 2025Guideline
- Pooled it
- Epidemiological investigation of a pertussis outbreak among schoolchildren in Burkina Faso, 2019.BMC research notes · 2025Article
- Whooping cough in the most vulnerable: A case series of pertussis in infants younger than three months in Qatar.Qatar medical journal · 2025Article
- The Present and Future Aspects of Life-Long Pertussis Prevention: Narrative Review with Regional Perspectives for Türkiye.Infectious diseases and therapy · 2023Review
- Evaluation of BioFire Respiratory Panel 2Microbiology spectrum · 2023Article
- The burden of viral lower respiratory tract infections during the neonatal period: six-year experience at a tertiary referral hospital.Croatian medical journal · 2022Article
- Clinical characteristics and etiology of children with bronchiolitis before and during the COVID-19 pandemic in Suzhou, China.Frontiers in pediatrics · 2022Article
- Clinical impact of respiratory syncytial virus infection on children hospitalized for pertussis.BMC infectious diseases · 2021Article
- Etiologies of Hospitalized Acute Bronchiolitis in Children 2 Years of Age and Younger: A 3 Years' Study During aFrontiers in pediatrics · 2021Article
- Bordetella and Bronchiolitis: A Chance Association or More Than That?Indian journal of pediatrics · 2018Article
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6 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the frequency of B. pertussis infection among young infants hospitalized with acute bronchiolitis and to determine whether B. pertussis infection affects the clinical course of acute bronchiolitis.
methodsA total of 172 infants <6 months of age hospitalized with acute bronchiolitis were tested for B. pertussis and respiratory viruses with real-time PCR. Cases were divided into 2 groups according to B. pertussis positive or negative. Clinical parameters, clinical severity scores and laboratory characteristics of the pertussis-positive and pertussis-negative cases were compared.
resultsBordetella pertussis infection was detected in 44 (25.6%) of the 172 infants hospitalized for acute bronchiolitis, and as co-infection with respiratory viral agents in 27 (61.4%) infants. Of the 44 pertussis-positive infants, only 17 (38.6%) experienced a paroxysmal cough, 13 (29.5%) had whooping and 15 (34.1%) had post-tussive vomiting. There was no significant difference between pertussis-positive and pertussis-negative infants according to Wang clinical score at admission (4.9 ± 1.5 vs. 5.2 ± 2.5; p = 0.689). The overall disease severity score was also similar between the two groups (6.5 ± 1.4 vs. 6.9 ± 1.6; p = 0.095).
conclusionsBordetella pertussis infection is common in young infants hospitalized for acute bronchiolitis, mostly as co-infection with respiratory viruses. The clinical features of pertussis in the infants are not characteristic. Viral bronchiolitis and pertussis cases could not be differentiated by clinical findings. Co-infection with pertussis did not affect the clinical outcome in infants hospitalized with acute bronchiolitis.
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