ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2019
Assessment of acute myocarditis by cardiac magnetic resonance imaging: Comparison of qualitative and quantitative analysis methods.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Diagnostic Performance of Extracellular Volume, Native T1, and T2 Mapping Versus Lake Louise Criteria by Cardiac Magnetic Resonance for Detection of Acute Myocarditis: A Meta-Analysis.Circulation. Cardiovascular imaging · 2018Pooled it
- Unmasking the Apex: Multimodality Imaging for the Evaluation of Left Ventricular Apical Obliteration.Diagnostics (Basel, Switzerland) · 2026Review
- Multimodal Imaging in the Diagnosis of Late-Stage Loeffler Endocarditis.JACC. Case reports · 2025Article
- A case report of right-sided heart failure secondary to JAK2-mutation Loeffler endocarditis.ESC heart failure · 2024Article
- Article
- Re-introducing immunotherapy in patients surviving immune checkpoint inhibitors-mediated myocarditis.Clinical research in cardiology : official journal of the German Cardiac Society · 2021Article
- Cardiac magnetic resonance imaging during the COVID-19 pandemic: A southern Italian single-center experience.European journal of radiology open · 2021Article
- Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2019: Positron emission tomography, computed tomography and magnetic resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Review
- Left Ventricular Mass in Hypertrophic Cardiomyopathy Assessed by 2D-Echocardiography: Validation with Magnetic Resonance Imaging.Journal of cardiovascular translational research · 2020Article
- The cardiac conundrum: a systematic review and bibliometric analysis of authorship in cardiac magnetic resonance imaging studies.Insights into imaging · 2020Review
- The search for water: Is it so easy to diagnose acute myocarditis?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
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Authors and funding
13 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundTo compare cardiac magnetic resonance (CMR) qualitative and quantitative analysis methods for the noninvasive assessment of myocardial inflammation in patients with suspected acute myocarditis (AM).
methodsA total of 61 patients with suspected AM underwent coronary angiography and CMR. Qualitative analysis was performed applying Lake-Louise Criteria (LLC), followed by quantitative analysis based on the evaluation of edema ratio (ER) and global relative enhancement (RE). Diagnostic performance was assessed for each method by measuring the area under the curves (AUC) of the receiver operating characteristic analyses. The final diagnosis of AM was based on symptoms and signs suggestive of cardiac disease, evidence of myocardial injury as defined by electrocardiogram changes, elevated troponin I, exclusion of coronary artery disease by coronary angiography, and clinical and echocardiographic follow-up at 3 months after admission to the chest pain unit.
resultsIn all patients, coronary angiography did not show significant coronary artery stenosis. Troponin I levels and creatine kinase were higher in patients with AM compared to those without (both P < .001). There were no significant differences among LLC, T2-weighted short inversion time inversion recovery (STIR) sequences, early (EGE), and late (LGE) gadolinium-enhancement sequences for diagnosis of AM. The AUC for qualitative (T2-weighted STIR 0.92, EGE 0.87 and LGE 0.88) and quantitative (ER 0.89 and global RE 0.80) analyses were also similar.
conclusionsQualitative and quantitative CMR analysis methods show similar diagnostic accuracy for the diagnosis of AM. These findings suggest that a simplified approach using a shortened CMR protocol including only T2-weighted STIR sequences might be useful to rule out AM in patients with acute coronary syndrome and normal coronary angiography.
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